Structural determinants of growth factor binding and specificity by VEGF receptor 2 Leppänen, V-M.; Prota, A.E.; Jeltsch, M.; Anisimov, A.; Kalkkinen, N.; Strandin, T.; Lankinen, H.; Goldman, A.; Ballmer-Hofer, K.; Alitalo, K. , Proc Natl Acad Sci U S A, 2010, (2010) Abstract

Activated forms of VEGF-C and VEGF-D provide improved vascular function in skeletal muscle Anisimov, A.; Alitalo, A.; Korpisalo, P.; Soronen, J.; Kaijalainen, S.; Leppänen, V.; Jeltsch, M.; Ylä-Herttuala, S.; Alitalo, K. , Circulation Research, Volume 104, p.1302-1312, (2009) Abstract

Overexpression of Vascular Endothelial Growth Factor-B in Mouse Heart Alters Cardiac Lipid Metabolism and Induces Myocardial Hypertrophy Karpanen, T.; Bry, M.; Ollila, H.M.; Seppänen-Laakso, T.; Liimatta, E.; Leskinen, H.; Kivelä, R.; Helkamaa, T.; Merentie, M.; Jeltsch, M.; Paavonen, K.; Andersson, L.C.; Mervaala, E.; Hassinen, I.E.; Ylä-Herttuala, S.; Ores, , Circulation Research, (2008) Abstract

Reevaluation of the role of VEGF-B suggests a restricted role in the revascularization of the ischemic myocardium Li, X.; Tjwa, M.; Van Hove, I.; Enholm, B.; Neven, E.; Paavonen, K.; Jeltsch, M.; Juan, T.D.; Sievers, R.E.; Chorianopoulos, E.; Wada, H.; Vanwildemeersch, M.; Noel, A.; Foidart, J.; Springer, M.L.; von De, , Arteriosclerosis, Thrombosis, and Vascular Biology, Volume 28, p.1614-20, (2008) Abstract

The tyrosine kinase inhibitor cediranib blocks ligand-induced vascular endothelial growth factor receptor-3 activity and lymphangiogenesis Heckman, C.A.; Holopainen, T.; Wirzenius, M.; Keskitalo, S.; Jeltsch, M.; Ylä-Herttuala, S.; Wedge, S.R.; Jürgensmeier, J.M.; Alitalo, K. , Cancer Research, Volume 68, p.4754-62, (2008) Abstract

Distinct architecture of lymphatic vessels induced by chimeric vascular endothelial growth factor-C/vascular endothelial growth factor heparin-binding domain fusion proteins Tammela, T.; He, Y.; Lyytikkä, J.; Jeltsch, M.; Markkanen, J.; Pajusola, K.; Ylä-Herttuala, S.; Alitalo, K. , Circulation Research, Volume 100, Issue 10, p.1468-75, (2007) Abstract

Enhanced capillary formation stimulated by a chimeric vascular endothelial growth factor/vascular endothelial growth factor-C silk domain fusion protein Keskitalo, S.; Tammela, T.; Lyytikka, J.; Karpanen, T.; Jeltsch, M.; Markkanen, J.; Yla-Herttuala, S.; Alitalo, K. , Circulation Research, Volume 100, Issue 10, p.1402-4, (2007) Abstract

Functional interaction of VEGF-C and VEGF-D with neuropilin receptors Karpanen, T.; Heckman, C.A.; Keskitalo, S.; Jeltsch, M.; Ollila, H.; Neufeld, G.; Tamagnone, L.; Alitalo, K. , FASEB J, Volume 20, Issue 9, Molecular/Cancer Biology Laboratory and Ludwig Institute for Cancer Research, Biomedicum Helsinki, P.O.B. 63, FI-00014 University of Helsinki, Helsinki, Finland, p.1462-72, (2006) Abstract

VEGF Receptors Jeltsch, M.; Alitalo, K. , Sigma-RBI Handbook of Receptor Classification and Signal Transduction, (2006) Abstract

VEGF/VEGF-C mosaic molecules reveal specificity determinants and feature novel receptor binding patterns Jeltsch, M.; Karpanen, T.; Strandin, T.; Aho, K.; Lankinen, H.; Alitalo, K. , J Biol Chem, Volume 281, Issue 17, Molecular/Cancer Biology Laboratory and Ludwig Institute for Cancer Research, Biomedicum Helsinki, Haartman Institute and Helsinki University Central Hospital, P.O. Box 63 (Haartmaninkatu 8), University of Helsinki, Helsinki 00014, Finland, p.12187-95, (2006) Abstract

Dual role of vascular endothelial growth factor in experimental obliterative bronchiolitis Krebs, R.; Tikkanen, J.M.; Nykanen, A.I.; Wood, J.; Jeltsch, M.; Yla-Herttuala, S.; Koskinen, P.K.; Lemstrom, K.B. , Am J Respir Crit Care Med, Volume 171, Issue 12, Cardiopulmonary Research Group, Transplantation Laboratory, University of Helsinki/Helsinki University Central Hospital, Helsinki, Finland, p.1421-9, (2005) Abstract

Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation Baluk, P.; Tammela, T.; Ator, E.; Lyubynska, N.; Achen, M.G.; Hicklin, D.J.; Jeltsch, M.; Petrova, T.V.; Pytowski, B.; Stacker, S.A.; Yla-Herttuala, S.; Jackson, D.G.; Alitalo, K.; McDonald, D.M. , J Clin Invest, Volume 115, Issue 2, Cardiovascular Research Institute, Comprehensive Cancer Center, and Department of Anatomy, UCSF, San Francisco, California 94143, USA, p.247-57, (2005) Abstract

Vascular endothelial cell growth factor receptor 3-mediated activation of lymphatic endothelium is crucial for tumor cell entry He, Y.; Rajantie, I.; Pajusola, K.; Jeltsch, M.; Holopainen, T.; Yla-Herttuala, S.; Harding, T.; Jooss, K.; Takahashi, T.; Alitalo, K. , Cancer Res, Volume 65, Issue 11, Molecular/Cancer Biology Laboratory and Ludwig Institute for Cancer Research, Biomedicum Helsinki and Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland, p.4739-46, (2005) Abstract

Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins Karkkainen, M.J.; Haiko, P.; Sainio, K.; Partanen, J.; Taipale, J.; Petrova, T.V.; Jeltsch, M.; Jackson, D.G.; Talikka, M.; Rauvala, H.; Betsholtz, C.; Alitalo, K. , Nat Immunol, Volume 5, Issue 1, Molecular/Cancer Biology Laboratory and Ludwig Institute for Cancer Research, Haartman Institute and Helsinki University Hospital, Biomedicum Helsinki, University of Helsinki, PO Box 63, 00014 Helsinki, Finland, p.74-80, (2004) Abstract

Genesis and pathogenesis of lymphatic vessels Jeltsch, M.; Tammela, T.; Alitalo, K.; Wilting, J. , Cell Tissue Res, Volume 314, Issue 1, Molecular and Cancer Biology Laboratory, Ludwig Institute for Cancer Research, and Helsinki University Central Hospital, Biomedicum Helsinki, University of Helsinki, Haartmaninkatu 8, Postbox 63, 00014, Helsinki, Finland, p.69-84, (2003) Abstract

Intrinsic versus microenvironmental regulation of lymphatic endothelial cell phenotype and function Veikkola, T.; Lohela, M.; Ikenberg, K.; Makinen, T.; Korff, T.; Saaristo, A.; Petrova, T.; Jeltsch, M.; Augustin, H.G.; Alitalo, K. , FASEB J, Volume 17, Issue 14, Molecular/Cancer Biology Laboratory and Ludwig Institute for Cancer Research, Biomedicum Helsinki, Haartman Institute and Helsinki University Central Hospital, 00014 University of Helsinki, Finland, p.2006-13, (2003) Abstract

VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia Gerhardt, H.; Golding, M.; Fruttiger, M.; Ruhrberg, C.; Lundkvist, r.; Abramsson, A.; Jeltsch, M.; Mitchell, C.; Alitalo, K.; Shima, D.; Betsholtz, C. , J Cell Biol, Volume 161, Issue 6, Deparrment of Medical Biochemistry, University of Goteborg, Medicinaregatan 9A, Box 440, SE 405 30 Goteborg, Sweden, p.1163-77, (2003) Abstract

Adenoviral VEGF-C overexpression induces blood vessel enlargement, tortuosity, and leakiness but no sprouting angiogenesis in th Saaristo, A.; Veikkola, T.; Enholm, B.; Hytonen, M.; Arola, J.; Pajusola, K.; Turunen, P.; Jeltsch, M.; Karkkainen, M.J.; Kerjaschki, D.; Bueler, H.; Yla-Herttuala, S.; Alitalo, K. , FASEB J, Volume 16, Issue 9, Molecular/Cancer Biology Laboratory and Ludwig Institute for Cancer Research, Biomedicum, University of Helsinki and Helsinki University Central Hospital, 00014 Helsinki, Finland, p.1041-9, (2002) Abstract

VEGFR-3 Ligands and Lymphangiogenesis Jeltsch, M. , PhD Thesis, University of Helsinki, (2002) Abstract

Adenoviral expression of vascular endothelial growth factor-C induces lymphangiogenesis in the skin Enholm, B.; Karpanen, T.; Jeltsch, M.; Kubo, H.; Stenback, F.; Prevo, R.; Jackson, D.G.; Yla-Herttuala, S.; Alitalo, K. , Circ Res, Volume 88, Issue 6, Molecular/Cancer Biology Laboratory and Ludvig Institute for Cancer Research, Haartman Institute, University of Helsinki, Finland, p.623-9, (2001) Abstract

Signalling via vascular endothelial growth factor receptor-3 is sufficient for lymphangiogenesis in transgenic mice Veikkola, T.; Jussila, L.; Makinen, T.; Karpanen, T.; Jeltsch, M.; Petrova, T.V.; Kubo, H.; Thurston, G.; McDonald, D.M.; Achen, M.G.; Stacker, S.A.; Alitalo, K. , EMBO J, Volume 20, Issue 6, Molecular/Cancer Biology Laboratory and Ludwig Institute for Cancer Research, Haartman Institute, University of Helsinki, PO Box 21 (Haartmaninkatu 3), 00014 Helsinki, Finland, p.1223-31, (2001) Abstract

Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis Mandriota, S.J.; Jussila, L.; Jeltsch, M.; Compagni, A.; Baetens, D.; Prevo, R.; Banerji, S.; Huarte, J.; Montesano, R.; Jackson, D.G.; Orci, L.; Alitalo, K.; Christofori, G.; Pepper, M.S. , EMBO J, Volume 20, Issue 4, Department of Morphology, University Medical Centre, 1 rue Michel Servet, 1211 Geneva 4, Switzerland, p.672-82, (2001) Abstract

Intravascular adenovirus-mediated VEGF-C gene transfer reduces neointima formation in balloon-denuded rabbit aorta Hiltunen, M.O.; Laitinen, M.; Turunen, M.P.; Jeltsch, M.; Hartikainen, J.; Rissanen, T.T.; Laukkanen, J.; Niemi, M.; Kossila, M.; Hakkinen, T.P.; Kivela, A.; Enholm, B.; Mansukoski, H.; Turunen, A.M.; Alitalo, K.; Yla-Herttuala, S. , Circulation, Volume 102, Issue 18, A.I. Virtanen Institute, University of Kuopio, Kuopio, Finland, p.2262-8, (2000) Abstract

Current biology of VEGF-B and VEGF-C Olofsson, B.; Jeltsch, M.; Eriksson, U.; Alitalo, K. , Curr Opin Biotechnol, Volume 10, Issue 6, Ludwig Institute for Cancer Research, Box 240, Stockholm, SE-171 77, Sweden, p.528-35, (1999) Abstract

Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (F Achen, M.G.; Jeltsch, M.; Kukk, E.; Makinen, T.; Vitali, A.; Wilks, A.F.; Alitalo, K.; Stacker, S.A. , Proc Natl Acad Sci U S A, Volume 95, Issue 2, Ludwig Institute for Cancer Research, Royal Melbourne Hospital, Victoria, Australia. Marc.achen@ludwig.edu.au, p.548-53, (1998) Abstract