@article {504,
	title = {Heterogeneity of the origin of the lymphatic system. [German].},
	journal = {Lymphologie in Forschung und Praxis},
	volume = {19},
	year = {2015},
	month = {12/2015},
	pages = {84-88},
	type = {Review},
	abstract = {The question {\textquotedblleft}How does the lymphatic system develop?{\textquotedblright} may be a simple one, but it is fundamental to our understanding of lymphatic malformations in children and the regeneration of lymphatics in adults. The question is by no means new and was already explored in the early 20 century. This resulted in a long-lasting controversy, which until recently had been far from being settled. The interest in the lymphatic system has greatly increased in recent years due to its implications in a variety of diseases. Several studies published this year address the heterogeneity of lymphatic endothelial cell development and unite previous controversially discussed data in a coherent model. These remarkable results, as well as the studies that paved their way, are discussed in this review.},
	issn = {1433-5255},
	url = {http://www.dglymph.de/fileadmin/global/pdfs/LymphForsch_2-15.pdf},
	author = {Mattonet, Kenny and Jeltsch, Michael}
}
@article {10,
	title = {Hyperplasia of lymphatic vessels in VEGF-C transgenic mice},
	journal = {Science (80- )},
	volume = {276},
	year = {1997},
	month = {1997/May/},
	pages = {1423 - 5},
	abstract = {No growth factors specific for the lymphatic vascular system have yet been described. Vascular endothelial growth factor (VEGF) regulates vascular permeability and angiogenesis, but does not promote lymphangiogenesis. Overexpression of VEGF-C, a ligand of the VEGF receptors VEGFR-3 and VEGFR-2, in the skin of transgenic mice resulted in lymphatic, but not vascular, endothelial proliferation and vessel enlargement. Thus, VEGF-C induces selective hyperplasia of the lymphatic vasculature, which is involved in the draining of interstitial fluid and in immune function, inflammation, and tumor metastasis. VEGF-C may play a role in disorders involving the lymphatic system and may be of potential use in therapeutic lymphangiogenesis.},
	url = {http://view.ncbi.nlm.nih.gov/pubmed/9162011},
	author = {Jeltsch, M and Kaipainen, A and Joukov, V and Meng, X and Lakso, M and Rauvala, H and Swartz, M and Fukumura, D and Jain, R K and Alitalo, K}
}
