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Alitalo, Kari
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A
Anisimov A
,
Alitalo A
,
Korpisalo P
,
Soronen J
,
Kaijalainen S
,
Leppänen V-M
, et al.
.
Activated forms of VEGF-C and VEGF-D provide improved vascular function in skeletal muscle
. Circ Res [Internet]. 2009;104(11):1302 - 12.
http://view.ncbi.nlm.nih.gov/pubmed/19443835
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Andrey Anisimov et al., Circulation Research 2009
(8.03 MB)
Andrey Anisimov et al., Circulation Research 2009, supplement
(5.9 MB)
Saaristo A
,
Veikkola T
,
Enholm B
,
Hytönen M
,
Arola J
,
Pajusola K
, et al.
.
Adenoviral VEGF-C overexpression induces blood vessel enlargement, tortuosity, and leakiness but no sprouting angiogenesis in the skin or mucous membranes
. FASEB J [Internet]. 2002;16(9):1041 - 9.
http://view.ncbi.nlm.nih.gov/pubmed/12087065
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Anne Saaristo et al., FASEB Journal 2002
(966.08 KB)
B
The basis for the distinct biological activities of vascular endothelial growth factor receptor-1 ligands
. Sci Signal. 2013;6(282):ra52.
PubMed
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Anisimov 2013 Science Signaling
(1.92 MB)
Anisimov 2013 Science Signaling Supplement
(2.09 MB)
C
CCBE1 enhances lymphangiogenesis via ADAMTS3-mediated VEGF-C activation
. Circulation [Internet]. 2014;129(19).
http://circ.ahajournals.org/content/early/2014/02/19/CIRCULATIONAHA.113.002779.abstract
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Postprint of Jeltsch et al. 2014 (Circulation): CCBE1 enhances lymphangiogenesis via ADAMTS3-mediated VEGF-C activation
(6.6 MB)
Postprint of Jeltsch et al. 2014 (Circulation): CCBE1 enhances lymphangiogenesis via ADAMTS3-mediated VEGF-C activation (Suppl.)
(2.38 MB)
Published version of Jeltsch et al. 2014 (Circulation): CCBE1 enhances lymphangiogenesis via ADAMTS3-mediated... (incl. suppl.)
(23.21 MB)
Saharinen P
,
Helotera H
,
Miettinen J
,
Norrmen C
,
D'Amico G
,
Jeltsch M
, et al.
.
Claudin-like protein 24 interacts with the VEGFR-2 and VEGFR-3 pathways and regulates lymphatic vessel development
. Genes Dev [Internet]. 2010;24(9):875 - 80.
http://view.ncbi.nlm.nih.gov/pubmed/20439428
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Pipsa Saharinen et al., Genes & Development 2010
(1.2 MB)
Pipsa Saharinen et al., Genes & Development 2010, supplement
(9.15 MB)
D
Tammela T
,
He Y
,
Lyytikkä J
,
Jeltsch M
,
Markkanen J
,
Pajusola K
, et al.
.
Distinct architecture of lymphatic vessels induced by chimeric vascular endothelial growth factor-C/vascular endothelial growth factor heparin-binding domain fusion proteins
. Circ Res [Internet]. 2007;100(10):1468 - 75.
http://view.ncbi.nlm.nih.gov/pubmed/17478733
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Tuomas Tammela et al., Circulation Research 2007
(1.1 MB)
E
Tvorogov D
,
Anisimov A
,
Zheng W
,
Leppänen V-M
,
Tammela T
,
Laurinavicius S
, et al.
.
Effective suppression of vascular network formation by combination of antibodies blocking VEGFR ligand binding and receptor dimerization
. Cancer Cell [Internet]. 2010;18(6):630 - 40.
http://view.ncbi.nlm.nih.gov/pubmed/21130043
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Denis Tvorogov et al., Cancer Cell 2010
(1.3 MB)
Denis Tvorogov et al., Cancer Cell 2010, supplement
(828.69 KB)
Efficient activation of the lymphangiogenic growth factor VEGF-C requires the C-terminal domain of VEGF-C and the N-terminal domain of CCBE1
. Scientific Reports [Internet]. 2017;7(1):4916.
https://www.nature.com/articles/s41598-017-04982-1
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Keskitalo S
,
Tammela T
,
Lyytikka J
,
Karpanen T
,
Jeltsch M
,
Markkanen J
, et al.
.
Enhanced capillary formation stimulated by a chimeric vascular endothelial growth factor/vascular endothelial growth factor-C silk domain fusion protein
. Circ Res [Internet]. 2007;100(10):1460 - 7.
http://view.ncbi.nlm.nih.gov/pubmed/17478734
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Salla Keskitalo et al., Circulation Research 2007
(1.98 MB)
F
Functional Dissection of the CCBE1 Protein: A Crucial Requirement for the Collagen Repeat Domain.
Circ Res [Internet]. 2015;116(10):1660-1669.
http://circres.ahajournals.org/content/116/10/1660.long
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Functional Importance of a Proteoglycan Co-Receptor in Pathologic Lymphangiogenesis
. Circulation Research [Internet]. 2016;119(2):210-221.
http://circres.ahajournals.org/content/early/2016/05/25/CIRCRESAHA.116.308504
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Johns et al. 2016: Functional Importance of a Proteoglycan Co-Receptor in Pathologic Lymphangiogenesis
(3.69 MB)
Johns et al. 2016: Functional Importance of a Proteoglycan Co-Receptor in Pathologic Lymphangiogenesis: Supplemental Data
(3.3 MB)
Kärpänen T
,
Heckman CA
,
Keskitalo S
,
Jeltsch M
,
Ollila H
,
Neufeld G
, et al.
.
Functional interaction of VEGF-C and VEGF-D with neuropilin receptors
. FASEB J [Internet]. 2006;20(9):1462 - 72.
http://view.ncbi.nlm.nih.gov/pubmed/16816121
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Terhi Kärpänen et al., FASEB Journal 2006
(2.51 MB)
G
Jeltsch M
,
Tammela T
,
Alitalo K
,
Wilting J
.
Genesis and pathogenesis of lymphatic vessels
. Cell Tissue Res [Internet]. 2003;314(1):69 - 84.
http://view.ncbi.nlm.nih.gov/pubmed/12942362
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Michael Jeltsch et al., Cell and Tissue Research 2003
(562.33 KB)
I
Veikkola T
,
Lohela M
,
Ikenberg K
,
Mäkinen T
,
Korff T
,
Saaristo A
, et al.
.
Intrinsic versus microenvironmental regulation of lymphatic endothelial cell phenotype and function
. FASEB J [Internet]. 2003;17(14):2006 - 13.
http://view.ncbi.nlm.nih.gov/pubmed/14597670
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Tanja Veikkola et al., FASEB Journal 2006
(598.77 KB)
K
Jha SK
,
Rauniyar K
,
Chronowska E
,
Mattonet K
,
Maina EW
,
Koistinen H
, et al.
.
KLK3/PSA and cathepsin D activate VEGF-C and VEGF-D
. eLife [Internet]. 2019;8:e44478.
https://elifesciences.org/articles/44478
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Jha & Rauniyar et al. 2019
(3.84 MB)
L
Jeltsch M
,
Alitalo K
.
Lymphatic-to-blood vessel transdifferentiation in zebrafish
. Nature Cardiovascular Research [Internet]. 2022;1(6):539 - 541.
https://rdcu.be/cOjJ0
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O
Karpanen T
,
Bry M
,
Ollila HM
,
Seppänen-Laakso T
,
Liimatta E
,
Leskinen H
, et al.
.
Overexpression of vascular endothelial growth factor-B in mouse heart alters cardiac lipid metabolism and induces myocardial hypertrophy
. Circ Res [Internet]. 2008;103(9):1018 - 26.
http://view.ncbi.nlm.nih.gov/pubmed/18757827
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Terhi Kärpänen et al., Circulation Research 2008
(898.27 KB)
Terhi Kärpänen et al., Circulation Research 2008, supplement
(1.56 MB)
P
Baluk P
,
Tammela T
,
Ator E
,
Lyubynska N
,
Achen MG
,
Hicklin DJ
, et al.
.
Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation
. J Clin Invest [Internet]. 2005;115(2):247 - 57.
http://view.ncbi.nlm.nih.gov/pubmed/15668734
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Peter Baluk et al., Journal of Clinical Investigation 2005
(1.89 MB)
R
Receptor Tyrosine Kinase-Mediated Angiogenesis
. Cold Spring Harbor Perspectives in Biology [Internet]. 2013;5(9).
http://cshperspectives.cshlp.org/content/5/9/a009183
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Jeltsch et al. (2013): Tyrosine Kinase-Mediated Angiogenesis. CSH Persp Biol
(934.46 KB)
Li X
,
Tjwa M
,
Van Hove I
,
Enholm B
,
Neven E
,
Paavonen K
, et al.
.
Reevaluation of the role of VEGF-B suggests a restricted role in the revascularization of the ischemic myocardium
. Arterioscler Thromb Vasc Biol [Internet]. 2008;28(9):1614 - 20.
http://view.ncbi.nlm.nih.gov/pubmed/18511699
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Xuri Li et al., Arteriosclerosis, Thrombosis, and Vascular Biology 2008
(738.26 KB)
Xuri Li et al., Arteriosclerosis, Thrombosis, and Vascular Biology 2008, data supplement
(1012.6 KB)
S
Structural and mechanistic insights into VEGF receptor 3 ligand binding and activation
. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2013;110(32):12960 - 12965.
http://www.pnas.org/content/110/32/12960.long
DOI
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Leppänen V-M
,
Prota AE
,
Jeltsch M
,
Anisimov A
,
Kalkkinen N
,
Strandin T
, et al.
.
Structural determinants of growth factor binding and specificity by VEGF receptor 2
. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2010;107(6):2425 - 30.
http://view.ncbi.nlm.nih.gov/pubmed/20145116
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Veli-Matti Leppänen et al. PNAS 2010
(1 MB)
Veli-Matti Leppänen et al. PNAS 2010, supporting information
(2.23 MB)
Leppänen V-M
,
Jeltsch M
,
Anisimov A
,
Tvorogov D
,
Aho K
,
Kalkkinen N
, et al.
.
Structural determinants of vascular endothelial growth factor-D receptor binding and specificity
. Blood [Internet]. 2011;117(5):1507 - 15.
http://view.ncbi.nlm.nih.gov/pubmed/21148085
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Veli-Matti Leppänen & Michael Jeltsch et al., Blood 2011
(1.17 MB)
Veli-Matti Leppänen & Michael Jeltsch et al. Blood 2011, supplementary data
(342.97 KB)
Albrecht I
,
Kopfstein L
,
Strittmatter K
,
Schomber T
,
Falkevall A
,
Hagberg CE
, et al.
.
Suppressive effects of vascular endothelial growth factor-B on tumor growth in a mouse model of pancreatic neuroendocrine tumorigenesis
. PLoS ONE [Internet]. 2010;5(11):e14109.
http://view.ncbi.nlm.nih.gov/pubmed/21124841
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Imke Albrecht et al., PLoS One 2010
(3.37 MB)
T
The TIE Receptor Family
. In Receptor Tyrosine Kinases: Family and Subfamilies [Internet]. Springer International Publishing; 2015. o 743-775.
https://link.springer.com/content/pdf/10.1007%2F978-3-319-11888-8_16.pdf
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