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A
Achen MG
,
Jeltsch M
,
Kukk E
,
Mäkinen T
,
Vitali A
,
Wilks AF
, et al.
.
Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4)
. Proc Natl Acad Sci U S A [Internet]. 1998;95(2):548 - 53.
http://view.ncbi.nlm.nih.gov/pubmed/9435229
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Marc Achen et al., PNAS 1998
(447.59 KB)
Albrecht I
,
Kopfstein L
,
Strittmatter K
,
Schomber T
,
Falkevall A
,
Hagberg CE
, et al.
.
Suppressive effects of vascular endothelial growth factor-B on tumor growth in a mouse model of pancreatic neuroendocrine tumorigenesis
. PLoS ONE [Internet]. 2010;5(11):e14109.
http://view.ncbi.nlm.nih.gov/pubmed/21124841
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Imke Albrecht et al., PLoS One 2010
(3.37 MB)
Anisimov A
,
Leppänen V-M
,
Tvorogov D
,
Zarkada G
,
Jeltsch M
,
Holopainen T
, et al.
.
The basis for the distinct biological activities of vascular endothelial growth factor receptor-1 ligands
. Sci Signal. 2013;6(282):ra52.
PubMed
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Anisimov 2013 Science Signaling
(1.92 MB)
Anisimov 2013 Science Signaling Supplement
(2.09 MB)
Anisimov A
,
Tvorogov D
,
Alitalo A
,
Leppänen V-M
,
An Y
,
Han EC
, et al.
.
Vascular endothelial growth factor-angiopoietin chimera with improved properties for therapeutic angiogenesis
. Circulation. 2013;127(4):424-434.
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Anisimov 2013
(6.56 MB)
Anisimov 2013 Supplement
(4.93 MB)
Anisimov A
,
Alitalo A
,
Korpisalo P
,
Soronen J
,
Kaijalainen S
,
Leppänen V-M
, et al.
.
Activated forms of VEGF-C and VEGF-D provide improved vascular function in skeletal muscle
. Circ Res [Internet]. 2009;104(11):1302 - 12.
http://view.ncbi.nlm.nih.gov/pubmed/19443835
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Andrey Anisimov et al., Circulation Research 2009
(8.03 MB)
Andrey Anisimov et al., Circulation Research 2009, supplement
(5.9 MB)
B
Baluk P
,
Tammela T
,
Ator E
,
Lyubynska N
,
Achen MG
,
Hicklin DJ
, et al.
.
Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation
. J Clin Invest [Internet]. 2005;115(2):247 - 57.
http://view.ncbi.nlm.nih.gov/pubmed/15668734
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Peter Baluk et al., Journal of Clinical Investigation 2005
(1.89 MB)
Batchu KChaithanya
,
Hokynar K
,
Jeltsch M
,
Mattonet K
,
Somerharju P
.
Substrate efflux propensity is the key determinant of iPLA-β-mediated glycerophospholipid hydrolysised
. Journal of Biological Chemistry [Internet]. 2015;.
http://www.jbc.org/content/early/2015/02/23/jbc.M115.642835.abstract
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J. Biol. Chem.-2015-Batchu-jbc.M115.642835.pdf
(786.13 KB)
Batchu KChaithanya
,
Hänninen S
,
Jha SKumar
,
Jeltsch M
,
Somerharju P
.
Factors regulating the substrate specificity of cytosolic phospholipase A2-alpha in vitro
. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 2016;1861(11):1597.
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Batchu et al. - 2016 - Factors regulating the substrate specificity of cy.pdf
(986.25 KB)
Bry M
,
Kivelä R
,
Holopainen T
,
Anisimov A
,
Tammela T
,
Soronen J
, et al.
.
Vascular endothelial growth factor-B acts as a coronary growth factor in transgenic rats without inducing angiogenesis, vascular leak, or inflammation
. Circulation [Internet]. 2010;122(17):1725 - 33.
http://view.ncbi.nlm.nih.gov/pubmed/20937974
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Maija Bry et al., Circulation 2010
(2.23 MB)
Maija Bry et al., Circulation 2010, supplement
(17.77 MB)
C
Chilov D
,
Kukk E
,
Taira S
,
Jeltsch M
,
Kaukonen J
,
Palotie A
, et al.
.
Genomic organization of human and mouse genes for vascular endothelial growth factor C
. J Biol Chem [Internet]. 1997;272(40):25176 - 83.
http://view.ncbi.nlm.nih.gov/pubmed/9312130
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Dmitry Chilov et al., The Journal of Biological Chemistry 1997
(517.68 KB)
D
Dashkevich A
,
Raissadati A
,
Syrjälä SO
,
Zarkada G
,
Keränen MAI
,
Tuuminen R
, et al.
.
Ischemia-Reperfusion Injury Enhances Lymphatic Endothelial VEGFR3 and Rejection in Cardiac Allografts
. American Journal of Transplantation [Internet]. 2015;16(4):1160-1172.
http://onlinelibrary.wiley.com/doi/10.1111/ajt.13564/abstract
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E
Enholm B
,
Karpanen T
,
Jeltsch M
,
Kubo H
,
Stenback F
,
Prevo R
, et al.
.
Adenoviral expression of vascular endothelial growth factor-C induces lymphangiogenesis in the skin
. Circ Res [Internet]. 2001;88(6):623 - 9.
http://view.ncbi.nlm.nih.gov/pubmed/11282897
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Bernd Enholm et al., Circulation Research 2001
(2.93 MB)
F
Fang S
,
Chen S
,
Nurmi H
,
Leppänen V-M
,
Jeltsch M
,
Scadden DT
, et al.
.
VEGF-C Protects the Integrity of Bone Marrow Perivascular Niche
. Blood [Internet]. 2020;:accepted - for publication.
https://ashpublications.org/blood/article/doi/10.1182/blood.2020005699/463465/VEGF-C-Protects-the-Integrity-of-Bone-Marrow
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Fang et al. 2020 - VEGF-C protects the integrity of bone marrow perivascular niche
(6 MB)
G
Gerhardt H
,
Golding M
,
Fruttiger M
,
Ruhrberg C
,
Lundkvist A
,
Abramsson A
, et al.
.
VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia
. J Cell Biol [Internet]. 2003;161(6):1163 - 77.
http://view.ncbi.nlm.nih.gov/pubmed/12810700
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Holger Gerhardt et al., The Journal of Biological Chemistry 2003
(2.24 MB)
Gucciardo E
,
Lehti TA
,
Korhonen A
,
Salvén P
,
Lehti K
,
Jeltsch M
, et al.
.
Lymphatics and the eye. [Finnish]
. Duodecim Lääketieteellinen Aikakauskirja [Internet]. 2020;136(16):1777-1788.
https://www.duodecimlehti.fi/lehti/2020/16/duo15739
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Gucciardo et al. Lymphatics and the Eye (English version).
(3.31 MB)
H
He Y
,
Rajantie I
,
Pajusola K
,
Jeltsch M
,
Holopainen T
,
Yla-Herttuala S
, et al.
.
Vascular endothelial cell growth factor receptor 3-mediated activation of lymphatic endothelium is crucial for tumor cell entry and spread via lymphatic vessels
. Cancer Res [Internet]. 2005;65(11):4739 - 46.
http://view.ncbi.nlm.nih.gov/pubmed/15930292
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Yulong He et al., Cancer Research 2005
(1.82 MB)
Heckman CA
,
Holopainen T
,
Wirzenius M
,
Keskitalo S
,
Jeltsch M
,
Ylä-Herttuala S
, et al.
.
The tyrosine kinase inhibitor cediranib blocks ligand-induced vascular endothelial growth factor receptor-3 activity and lymphangiogenesis
. Cancer Res [Internet]. 2008;68(12):4754 - 62.
http://view.ncbi.nlm.nih.gov/pubmed/18559522
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Caroline Heckman et al., Cancer Research 2008
(504.8 KB)
Heckman CA
,
Holopainen T
,
Wirzenius M
,
Keskitalo S
,
Jeltsch M
,
Wedge SR
, et al.
.
Inhibiton of VEGF-C-induced VEGFR-3 activity and lymphatic endothelial cell function by the tyrosine kinase inhibitor AZD2171
. In 98th Annual Meeting of the American-Association-for-Cancer-Research [Internet]. Los Angeles, CA: American Association for Cancer Research; 2007.
http://dx.doi.org/10.1158/0008-5472.CAN-07-5809
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Heckman et al. - 2007 - Inhibiton of VEGF-C-induced VEGFR-3 activity and l.pdf
(236.37 KB)
Hiltunen MO
,
Laitinen M
,
Turunen MP
,
Jeltsch M
,
Hartikainen J
,
Rissanen TT
, et al.
.
Intravascular adenovirus-mediated VEGF-C gene transfer reduces neointima formation in balloon-denuded rabbit aorta
. Circulation [Internet]. 2000;102(18):2262 - 8.
http://view.ncbi.nlm.nih.gov/pubmed/11056103
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Mikko Hiltunen et al., Circulation 2000
(1.44 MB)
J
Jeltsch M
,
Karpanen T
,
Strandin T
,
Aho K
,
Lankinen H
,
Alitalo K
.
Vascular endothelial growth factor (VEGF)/VEGF-C mosaic molecules reveal specificity determinants and feature novel receptor binding patterns
. J Biol Chem [Internet]. 2006;281(17):12187 - 95.
http://view.ncbi.nlm.nih.gov/pubmed/16505489
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Michael Jeltsch et al., The Journal of Biological Chemistry 2006
(1.04 MB)
Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 1
(1.01 MB)
Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 2
(596.06 KB)
Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 3
(738.98 KB)
Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 4
(710.03 KB)
Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 5
(163.64 KB)
Jeltsch M
.
Lymphangiogenesis in Health and Disease
[Internet]. 41st European Societry of Lymphology (ESL) Congress. Lausanne, Switzerland: European Group of Lymphology; 2015.
http://www.eurolymphology.org/JOURNAL/VOL26-N72-2015/#p=10
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Abstract of the Presentation (Michael Jeltsch)
(75.34 KB)
Jeltsch M
.
From Molecular Genetics and Biology to Effective Treatments of Lymphatic Disorders
[Internet]. 42nd Congress of the European Society of Lymphology. Mulhouse, France; 2016.
http://www.eurolymphology.org/JOURNAL/VOL28-N74-2016/#p=14
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Jeltsch 2016: From Molecular Genetics and Biology to Effective Treatments of Lymphatic Disorders
(683.85 KB)
Jeltsch M
.
What you should know about VEGF-C when working with lymphatics [German]
. In Lymphologie 2017 [Internet]. Bad Soden (Frankfurt), Germany; 2017.
https://jeltsch.org/Abstrakt-BadSoden2017
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Extended Abstract (published in Vasomed, 2018)
(226.5 KB)
Jeltsch M
,
Tammela T
,
Alitalo K
,
Wilting J
.
Genesis and pathogenesis of lymphatic vessels
. Cell Tissue Res [Internet]. 2003;314(1):69 - 84.
http://view.ncbi.nlm.nih.gov/pubmed/12942362
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Michael Jeltsch et al., Cell and Tissue Research 2003
(562.33 KB)
Jeltsch M
,
Alitalo K
.
VEGF Receptors
. In Sigma-RBI Handbook of Receptor Classification and Signal Transduction [Internet]. 5.th ed. Sigma; 2006.
http://www.sigmaaldrich.com/technical-documents/articles/biology/rbi-handbook.html
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Sigma-RBI Handbook of Receptor Classification and Signal Transduction: VEGF Receptors
(263.92 KB)
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