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A
Anisimov A
,
Alitalo A
,
Korpisalo P
,
Soronen J
,
Kaijalainen S
,
Leppänen V-M
, et al.
.
Activated forms of VEGF-C and VEGF-D provide improved vascular function in skeletal muscle
. Circ Res [Internet]. 2009;104(11):1302 - 12.
http://view.ncbi.nlm.nih.gov/pubmed/19443835
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Andrey Anisimov et al., Circulation Research 2009
(8.03 MB)
Andrey Anisimov et al., Circulation Research 2009, supplement
(5.9 MB)
Anisimov A
,
Alitalo A
,
Korpisalo P
,
Soronen J
,
Kaijalainen S
,
Leppänen V-M
, et al.
.
Activated forms of VEGF-C and VEGF-D provide improved vascular function in skeletal muscle
. Circ Res [Internet]. 2009;104(11):1302 - 12.
http://view.ncbi.nlm.nih.gov/pubmed/19443835
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Andrey Anisimov et al., Circulation Research 2009
(8.03 MB)
Andrey Anisimov et al., Circulation Research 2009, supplement
(5.9 MB)
Anisimov A
,
Alitalo A
,
Korpisalo P
,
Soronen J
,
Kaijalainen S
,
Leppänen V-M
, et al.
.
Activated forms of VEGF-C and VEGF-D provide improved vascular function in skeletal muscle
. Circ Res [Internet]. 2009;104(11):1302 - 12.
http://view.ncbi.nlm.nih.gov/pubmed/19443835
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Andrey Anisimov et al., Circulation Research 2009
(8.03 MB)
Andrey Anisimov et al., Circulation Research 2009, supplement
(5.9 MB)
Enholm B
,
Karpanen T
,
Jeltsch M
,
Kubo H
,
Stenback F
,
Prevo R
, et al.
.
Adenoviral expression of vascular endothelial growth factor-C induces lymphangiogenesis in the skin
. Circ Res [Internet]. 2001;88(6):623 - 9.
http://view.ncbi.nlm.nih.gov/pubmed/11282897
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Bernd Enholm et al., Circulation Research 2001
(2.93 MB)
Saaristo A
,
Veikkola T
,
Enholm B
,
Hytönen M
,
Arola J
,
Pajusola K
, et al.
.
Adenoviral VEGF-C overexpression induces blood vessel enlargement, tortuosity, and leakiness but no sprouting angiogenesis in the skin or mucous membranes
. FASEB J [Internet]. 2002;16(9):1041 - 9.
http://view.ncbi.nlm.nih.gov/pubmed/12087065
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Anne Saaristo et al., FASEB Journal 2002
(966.08 KB)
Saaristo A
,
Veikkola T
,
Enholm B
,
Hytönen M
,
Arola J
,
Pajusola K
, et al.
.
Adenoviral VEGF-C overexpression induces blood vessel enlargement, tortuosity, and leakiness but no sprouting angiogenesis in the skin or mucous membranes
. FASEB J [Internet]. 2002;16(9):1041 - 9.
http://view.ncbi.nlm.nih.gov/pubmed/12087065
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Anne Saaristo et al., FASEB Journal 2002
(966.08 KB)
B
Anisimov A
,
Leppänen V-M
,
Tvorogov D
,
Zarkada G
,
Jeltsch M
,
Holopainen T
, et al.
.
The basis for the distinct biological activities of vascular endothelial growth factor receptor-1 ligands
. Sci Signal. 2013;6(282):ra52.
PubMed
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Anisimov 2013 Science Signaling
(1.92 MB)
Anisimov 2013 Science Signaling Supplement
(2.09 MB)
Anisimov A
,
Leppänen V-M
,
Tvorogov D
,
Zarkada G
,
Jeltsch M
,
Holopainen T
, et al.
.
The basis for the distinct biological activities of vascular endothelial growth factor receptor-1 ligands
. Sci Signal. 2013;6(282):ra52.
PubMed
DOI
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Anisimov 2013 Science Signaling
(1.92 MB)
Anisimov 2013 Science Signaling Supplement
(2.09 MB)
C
Jeltsch M
,
Jha SKumar
,
Tvorogov D
,
Anisimov A
,
Leppänen V-M
,
Holopainen T
, et al.
.
CCBE1 enhances lymphangiogenesis via ADAMTS3-mediated VEGF-C activation
. Circulation [Internet]. 2014;129(19).
http://circ.ahajournals.org/content/early/2014/02/19/CIRCULATIONAHA.113.002779.abstract
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Postprint of Jeltsch et al. 2014 (Circulation): CCBE1 enhances lymphangiogenesis via ADAMTS3-mediated VEGF-C activation
(6.6 MB)
Postprint of Jeltsch et al. 2014 (Circulation): CCBE1 enhances lymphangiogenesis via ADAMTS3-mediated VEGF-C activation (Suppl.)
(2.38 MB)
Published version of Jeltsch et al. 2014 (Circulation): CCBE1 enhances lymphangiogenesis via ADAMTS3-mediated... (incl. suppl.)
(23.21 MB)
Jeltsch M
,
Jha SKumar
,
Tvorogov D
,
Anisimov A
,
Leppänen V-M
,
Holopainen T
, et al.
.
CCBE1 enhances lymphangiogenesis via ADAMTS3-mediated VEGF-C activation
. Circulation [Internet]. 2014;129(19).
http://circ.ahajournals.org/content/early/2014/02/19/CIRCULATIONAHA.113.002779.abstract
DOI
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Postprint of Jeltsch et al. 2014 (Circulation): CCBE1 enhances lymphangiogenesis via ADAMTS3-mediated VEGF-C activation
(6.6 MB)
Postprint of Jeltsch et al. 2014 (Circulation): CCBE1 enhances lymphangiogenesis via ADAMTS3-mediated VEGF-C activation (Suppl.)
(2.38 MB)
Published version of Jeltsch et al. 2014 (Circulation): CCBE1 enhances lymphangiogenesis via ADAMTS3-mediated... (incl. suppl.)
(23.21 MB)
Saharinen P
,
Helotera H
,
Miettinen J
,
Norrmen C
,
D'Amico G
,
Jeltsch M
, et al.
.
Claudin-like protein 24 interacts with the VEGFR-2 and VEGFR-3 pathways and regulates lymphatic vessel development
. Genes Dev [Internet]. 2010;24(9):875 - 80.
http://view.ncbi.nlm.nih.gov/pubmed/20439428
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Pipsa Saharinen et al., Genes & Development 2010
(1.2 MB)
Pipsa Saharinen et al., Genes & Development 2010, supplement
(9.15 MB)
Olofsson B
,
Jeltsch M
,
Eriksson U
,
Alitalo K
.
Current biology of VEGF-B and VEGF-C
. Curr Opin Biotechnol [Internet]. 1999;10(6):528 - 35.
http://view.ncbi.nlm.nih.gov/pubmed/10600689
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Birgitta Olofsson et al., Current Opinion in Biotechnology 1999
(577.33 KB)
D
Tammela T
,
He Y
,
Lyytikkä J
,
Jeltsch M
,
Markkanen J
,
Pajusola K
, et al.
.
Distinct architecture of lymphatic vessels induced by chimeric vascular endothelial growth factor-C/vascular endothelial growth factor heparin-binding domain fusion proteins
. Circ Res [Internet]. 2007;100(10):1468 - 75.
http://view.ncbi.nlm.nih.gov/pubmed/17478733
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Tuomas Tammela et al., Circulation Research 2007
(1.1 MB)
E
Tvorogov D
,
Anisimov A
,
Zheng W
,
Leppänen V-M
,
Tammela T
,
Laurinavicius S
, et al.
.
Effective suppression of vascular network formation by combination of antibodies blocking VEGFR ligand binding and receptor dimerization
. Cancer Cell [Internet]. 2010;18(6):630 - 40.
http://view.ncbi.nlm.nih.gov/pubmed/21130043
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Denis Tvorogov et al., Cancer Cell 2010
(1.3 MB)
Denis Tvorogov et al., Cancer Cell 2010, supplement
(828.69 KB)
Tvorogov D
,
Anisimov A
,
Zheng W
,
Leppänen V-M
,
Tammela T
,
Laurinavicius S
, et al.
.
Effective suppression of vascular network formation by combination of antibodies blocking VEGFR ligand binding and receptor dimerization
. Cancer Cell [Internet]. 2010;18(6):630 - 40.
http://view.ncbi.nlm.nih.gov/pubmed/21130043
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Denis Tvorogov et al., Cancer Cell 2010
(1.3 MB)
Denis Tvorogov et al., Cancer Cell 2010, supplement
(828.69 KB)
Jha SK
,
Rauniyar K
,
Kärpänen T
,
Leppänen V-M
,
Brouillard P
,
Vikkula M
, et al.
.
Efficient activation of the lymphangiogenic growth factor VEGF-C requires the C-terminal domain of VEGF-C and the N-terminal domain of CCBE1
. Scientific Reports [Internet]. 2017;7(1):4916.
https://www.nature.com/articles/s41598-017-04982-1
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Keskitalo S
,
Tammela T
,
Lyytikka J
,
Karpanen T
,
Jeltsch M
,
Markkanen J
, et al.
.
Enhanced capillary formation stimulated by a chimeric vascular endothelial growth factor/vascular endothelial growth factor-C silk domain fusion protein
. Circ Res [Internet]. 2007;100(10):1460 - 7.
http://view.ncbi.nlm.nih.gov/pubmed/17478734
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Salla Keskitalo et al., Circulation Research 2007
(1.98 MB)
F
M Roukens G
,
Peterson-Maduro J
,
Padberg Y
,
Jeltsch M
,
Leppänen V-M
,
Bos FL
, et al.
.
Functional Dissection of the CCBE1 Protein: A Crucial Requirement for the Collagen Repeat Domain.
Circ Res [Internet]. 2015;116(10):1660-1669.
http://circres.ahajournals.org/content/116/10/1660.long
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Johns SC
,
Yin X
,
Jeltsch M
,
Bishop JR
,
Schuksz M
,
Ghazal REl
, et al.
.
Functional Importance of a Proteoglycan Co-Receptor in Pathologic Lymphangiogenesis
. Circulation Research [Internet]. 2016;119(2):210-221.
http://circres.ahajournals.org/content/early/2016/05/25/CIRCRESAHA.116.308504
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Johns et al. 2016: Functional Importance of a Proteoglycan Co-Receptor in Pathologic Lymphangiogenesis
(3.69 MB)
Johns et al. 2016: Functional Importance of a Proteoglycan Co-Receptor in Pathologic Lymphangiogenesis: Supplemental Data
(3.3 MB)
Kärpänen T
,
Heckman CA
,
Keskitalo S
,
Jeltsch M
,
Ollila H
,
Neufeld G
, et al.
.
Functional interaction of VEGF-C and VEGF-D with neuropilin receptors
. FASEB J [Internet]. 2006;20(9):1462 - 72.
http://view.ncbi.nlm.nih.gov/pubmed/16816121
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Terhi Kärpänen et al., FASEB Journal 2006
(2.51 MB)
G
Jeltsch M
,
Tammela T
,
Alitalo K
,
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.
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. Cell Tissue Res [Internet]. 2003;314(1):69 - 84.
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Michael Jeltsch et al., Cell and Tissue Research 2003
(562.33 KB)
Chilov D
,
Kukk E
,
Taira S
,
Jeltsch M
,
Kaukonen J
,
Palotie A
, et al.
.
Genomic organization of human and mouse genes for vascular endothelial growth factor C
. J Biol Chem [Internet]. 1997;272(40):25176 - 83.
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Dmitry Chilov et al., The Journal of Biological Chemistry 1997
(517.68 KB)
H
Jeltsch M
,
Kaipainen A
,
Joukov V
,
Meng X
,
Lakso M
,
Rauvala H
, et al.
.
Hyperplasia of lymphatic vessels in VEGF-C transgenic mice
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Michael Jeltsch et al., Science 1997
(293.65 KB)
I
Hiltunen MO
,
Laitinen M
,
Turunen MP
,
Jeltsch M
,
Hartikainen J
,
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, et al.
.
Intravascular adenovirus-mediated VEGF-C gene transfer reduces neointima formation in balloon-denuded rabbit aorta
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Mikko Hiltunen et al., Circulation 2000
(1.44 MB)
Veikkola T
,
Lohela M
,
Ikenberg K
,
Mäkinen T
,
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,
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, et al.
.
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. FASEB J [Internet]. 2003;17(14):2006 - 13.
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Tanja Veikkola et al., FASEB Journal 2006
(598.77 KB)
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