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Mandriota SJ
,
Jussila L
,
Jeltsch M
,
Compagni A
,
Baetens D
,
Prevo R
, et al.
.
Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis
. EMBO J [Internet]. 2001;20(4):672 - 82.
http://view.ncbi.nlm.nih.gov/pubmed/11179212
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Stefano Mandriota et al., EMBO Journal 2001
(736.96 KB)
Bry M
,
Kivelä R
,
Holopainen T
,
Anisimov A
,
Tammela T
,
Soronen J
, et al.
.
Vascular endothelial growth factor-B acts as a coronary growth factor in transgenic rats without inducing angiogenesis, vascular leak, or inflammation
. Circulation [Internet]. 2010;122(17):1725 - 33.
http://view.ncbi.nlm.nih.gov/pubmed/20937974
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Maija Bry et al., Circulation 2010
(2.23 MB)
Maija Bry et al., Circulation 2010, supplement
(17.77 MB)
Karkkainen MJ
,
Haiko P
,
Sainio K
,
Partanen J
,
Taipale J
,
Petrova TV
, et al.
.
Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins
. Nat Immunol [Internet]. 2004;5(1):74 - 80.
http://view.ncbi.nlm.nih.gov/pubmed/14634646
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Marika Kärkkäinen et al., Nature Immunology 2004
(3.01 MB)
Marika Kärkkäinen et al., Nature Immunology 2004, supplementary data 1
(1.27 MB)
Marika Kärkkäinen et al., Nature Immunology 2004, supplementary data 2
(1.23 MB)
He Y
,
Rajantie I
,
Pajusola K
,
Jeltsch M
,
Holopainen T
,
Yla-Herttuala S
, et al.
.
Vascular endothelial cell growth factor receptor 3-mediated activation of lymphatic endothelium is crucial for tumor cell entry and spread via lymphatic vessels
. Cancer Res [Internet]. 2005;65(11):4739 - 46.
http://view.ncbi.nlm.nih.gov/pubmed/15930292
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Yulong He et al., Cancer Research 2005
(1.82 MB)
He Y
,
Rajantie I
,
Pajusola K
,
Jeltsch M
,
Holopainen T
,
Yla-Herttuala S
, et al.
.
Vascular endothelial cell growth factor receptor 3-mediated activation of lymphatic endothelium is crucial for tumor cell entry and spread via lymphatic vessels
. Cancer Res [Internet]. 2005;65(11):4739 - 46.
http://view.ncbi.nlm.nih.gov/pubmed/15930292
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Yulong He et al., Cancer Research 2005
(1.82 MB)
He Y
,
Rajantie I
,
Pajusola K
,
Jeltsch M
,
Holopainen T
,
Yla-Herttuala S
, et al.
.
Vascular endothelial cell growth factor receptor 3-mediated activation of lymphatic endothelium is crucial for tumor cell entry and spread via lymphatic vessels
. Cancer Res [Internet]. 2005;65(11):4739 - 46.
http://view.ncbi.nlm.nih.gov/pubmed/15930292
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Yulong He et al., Cancer Research 2005
(1.82 MB)
T
Heckman CA
,
Holopainen T
,
Wirzenius M
,
Keskitalo S
,
Jeltsch M
,
Ylä-Herttuala S
, et al.
.
The tyrosine kinase inhibitor cediranib blocks ligand-induced vascular endothelial growth factor receptor-3 activity and lymphangiogenesis
. Cancer Res [Internet]. 2008;68(12):4754 - 62.
http://view.ncbi.nlm.nih.gov/pubmed/18559522
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Caroline Heckman et al., Cancer Research 2008
(504.8 KB)
Heckman CA
,
Holopainen T
,
Wirzenius M
,
Keskitalo S
,
Jeltsch M
,
Ylä-Herttuala S
, et al.
.
The tyrosine kinase inhibitor cediranib blocks ligand-induced vascular endothelial growth factor receptor-3 activity and lymphangiogenesis
. Cancer Res [Internet]. 2008;68(12):4754 - 62.
http://view.ncbi.nlm.nih.gov/pubmed/18559522
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Caroline Heckman et al., Cancer Research 2008
(504.8 KB)
S
Albrecht I
,
Kopfstein L
,
Strittmatter K
,
Schomber T
,
Falkevall A
,
Hagberg CE
, et al.
.
Suppressive effects of vascular endothelial growth factor-B on tumor growth in a mouse model of pancreatic neuroendocrine tumorigenesis
. PLoS ONE [Internet]. 2010;5(11):e14109.
http://view.ncbi.nlm.nih.gov/pubmed/21124841
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Imke Albrecht et al., PLoS One 2010
(3.37 MB)
P
Baluk P
,
Tammela T
,
Ator E
,
Lyubynska N
,
Achen MG
,
Hicklin DJ
, et al.
.
Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation
. J Clin Invest [Internet]. 2005;115(2):247 - 57.
http://view.ncbi.nlm.nih.gov/pubmed/15668734
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Peter Baluk et al., Journal of Clinical Investigation 2005
(1.89 MB)
O
Karpanen T
,
Bry M
,
Ollila HM
,
Seppänen-Laakso T
,
Liimatta E
,
Leskinen H
, et al.
.
Overexpression of vascular endothelial growth factor-B in mouse heart alters cardiac lipid metabolism and induces myocardial hypertrophy
. Circ Res [Internet]. 2008;103(9):1018 - 26.
http://view.ncbi.nlm.nih.gov/pubmed/18757827
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Terhi Kärpänen et al., Circulation Research 2008
(898.27 KB)
Terhi Kärpänen et al., Circulation Research 2008, supplement
(1.56 MB)
Karpanen T
,
Bry M
,
Ollila HM
,
Seppänen-Laakso T
,
Liimatta E
,
Leskinen H
, et al.
.
Overexpression of vascular endothelial growth factor-B in mouse heart alters cardiac lipid metabolism and induces myocardial hypertrophy
. Circ Res [Internet]. 2008;103(9):1018 - 26.
http://view.ncbi.nlm.nih.gov/pubmed/18757827
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Terhi Kärpänen et al., Circulation Research 2008
(898.27 KB)
Terhi Kärpänen et al., Circulation Research 2008, supplement
(1.56 MB)
I
Hiltunen MO
,
Laitinen M
,
Turunen MP
,
Jeltsch M
,
Hartikainen J
,
Rissanen TT
, et al.
.
Intravascular adenovirus-mediated VEGF-C gene transfer reduces neointima formation in balloon-denuded rabbit aorta
. Circulation [Internet]. 2000;102(18):2262 - 8.
http://view.ncbi.nlm.nih.gov/pubmed/11056103
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Mikko Hiltunen et al., Circulation 2000
(1.44 MB)
Hiltunen MO
,
Laitinen M
,
Turunen MP
,
Jeltsch M
,
Hartikainen J
,
Rissanen TT
, et al.
.
Intravascular adenovirus-mediated VEGF-C gene transfer reduces neointima formation in balloon-denuded rabbit aorta
. Circulation [Internet]. 2000;102(18):2262 - 8.
http://view.ncbi.nlm.nih.gov/pubmed/11056103
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Mikko Hiltunen et al., Circulation 2000
(1.44 MB)
Hiltunen MO
,
Laitinen M
,
Turunen MP
,
Jeltsch M
,
Hartikainen J
,
Rissanen TT
, et al.
.
Intravascular adenovirus-mediated VEGF-C gene transfer reduces neointima formation in balloon-denuded rabbit aorta
. Circulation [Internet]. 2000;102(18):2262 - 8.
http://view.ncbi.nlm.nih.gov/pubmed/11056103
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Mikko Hiltunen et al., Circulation 2000
(1.44 MB)
F
Kärpänen T
,
Heckman CA
,
Keskitalo S
,
Jeltsch M
,
Ollila H
,
Neufeld G
, et al.
.
Functional interaction of VEGF-C and VEGF-D with neuropilin receptors
. FASEB J [Internet]. 2006;20(9):1462 - 72.
http://view.ncbi.nlm.nih.gov/pubmed/16816121
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Terhi Kärpänen et al., FASEB Journal 2006
(2.51 MB)
E
Tvorogov D
,
Anisimov A
,
Zheng W
,
Leppänen V-M
,
Tammela T
,
Laurinavicius S
, et al.
.
Effective suppression of vascular network formation by combination of antibodies blocking VEGFR ligand binding and receptor dimerization
. Cancer Cell [Internet]. 2010;18(6):630 - 40.
http://view.ncbi.nlm.nih.gov/pubmed/21130043
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Denis Tvorogov et al., Cancer Cell 2010
(1.3 MB)
Denis Tvorogov et al., Cancer Cell 2010, supplement
(828.69 KB)
Tvorogov D
,
Anisimov A
,
Zheng W
,
Leppänen V-M
,
Tammela T
,
Laurinavicius S
, et al.
.
Effective suppression of vascular network formation by combination of antibodies blocking VEGFR ligand binding and receptor dimerization
. Cancer Cell [Internet]. 2010;18(6):630 - 40.
http://view.ncbi.nlm.nih.gov/pubmed/21130043
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Denis Tvorogov et al., Cancer Cell 2010
(1.3 MB)
Denis Tvorogov et al., Cancer Cell 2010, supplement
(828.69 KB)
Tvorogov D
,
Anisimov A
,
Zheng W
,
Leppänen V-M
,
Tammela T
,
Laurinavicius S
, et al.
.
Effective suppression of vascular network formation by combination of antibodies blocking VEGFR ligand binding and receptor dimerization
. Cancer Cell [Internet]. 2010;18(6):630 - 40.
http://view.ncbi.nlm.nih.gov/pubmed/21130043
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Denis Tvorogov et al., Cancer Cell 2010
(1.3 MB)
Denis Tvorogov et al., Cancer Cell 2010, supplement
(828.69 KB)
D
Tammela T
,
He Y
,
Lyytikkä J
,
Jeltsch M
,
Markkanen J
,
Pajusola K
, et al.
.
Distinct architecture of lymphatic vessels induced by chimeric vascular endothelial growth factor-C/vascular endothelial growth factor heparin-binding domain fusion proteins
. Circ Res [Internet]. 2007;100(10):1468 - 75.
http://view.ncbi.nlm.nih.gov/pubmed/17478733
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Tuomas Tammela et al., Circulation Research 2007
(1.1 MB)
C
Saharinen P
,
Helotera H
,
Miettinen J
,
Norrmen C
,
D'Amico G
,
Jeltsch M
, et al.
.
Claudin-like protein 24 interacts with the VEGFR-2 and VEGFR-3 pathways and regulates lymphatic vessel development
. Genes Dev [Internet]. 2010;24(9):875 - 80.
http://view.ncbi.nlm.nih.gov/pubmed/20439428
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Pipsa Saharinen et al., Genes & Development 2010
(1.2 MB)
Pipsa Saharinen et al., Genes & Development 2010, supplement
(9.15 MB)
A
Saaristo A
,
Veikkola T
,
Enholm B
,
Hytönen M
,
Arola J
,
Pajusola K
, et al.
.
Adenoviral VEGF-C overexpression induces blood vessel enlargement, tortuosity, and leakiness but no sprouting angiogenesis in the skin or mucous membranes
. FASEB J [Internet]. 2002;16(9):1041 - 9.
http://view.ncbi.nlm.nih.gov/pubmed/12087065
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Anne Saaristo et al., FASEB Journal 2002
(966.08 KB)