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A
Anisimov A
,
Alitalo A
,
Korpisalo P
,
Soronen J
,
Kaijalainen S
,
Leppänen V-M
, et al.
.
Activated forms of VEGF-C and VEGF-D provide improved vascular function in skeletal muscle
. Circ Res [Internet]. 2009;104(11):1302 - 12.
http://view.ncbi.nlm.nih.gov/pubmed/19443835
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Andrey Anisimov et al., Circulation Research 2009
(8.03 MB)
Andrey Anisimov et al., Circulation Research 2009, supplement
(5.9 MB)
Anisimov A
,
Alitalo A
,
Korpisalo P
,
Soronen J
,
Kaijalainen S
,
Leppänen V-M
, et al.
.
Activated forms of VEGF-C and VEGF-D provide improved vascular function in skeletal muscle
. Circ Res [Internet]. 2009;104(11):1302 - 12.
http://view.ncbi.nlm.nih.gov/pubmed/19443835
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Andrey Anisimov et al., Circulation Research 2009
(8.03 MB)
Andrey Anisimov et al., Circulation Research 2009, supplement
(5.9 MB)
Enholm B
,
Karpanen T
,
Jeltsch M
,
Kubo H
,
Stenback F
,
Prevo R
, et al.
.
Adenoviral expression of vascular endothelial growth factor-C induces lymphangiogenesis in the skin
. Circ Res [Internet]. 2001;88(6):623 - 9.
http://view.ncbi.nlm.nih.gov/pubmed/11282897
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Bernd Enholm et al., Circulation Research 2001
(2.93 MB)
Enholm B
,
Karpanen T
,
Jeltsch M
,
Kubo H
,
Stenback F
,
Prevo R
, et al.
.
Adenoviral expression of vascular endothelial growth factor-C induces lymphangiogenesis in the skin
. Circ Res [Internet]. 2001;88(6):623 - 9.
http://view.ncbi.nlm.nih.gov/pubmed/11282897
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Bernd Enholm et al., Circulation Research 2001
(2.93 MB)
Saaristo A
,
Veikkola T
,
Enholm B
,
Hytönen M
,
Arola J
,
Pajusola K
, et al.
.
Adenoviral VEGF-C overexpression induces blood vessel enlargement, tortuosity, and leakiness but no sprouting angiogenesis in the skin or mucous membranes
. FASEB J [Internet]. 2002;16(9):1041 - 9.
http://view.ncbi.nlm.nih.gov/pubmed/12087065
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Anne Saaristo et al., FASEB Journal 2002
(966.08 KB)
Saaristo A
,
Veikkola T
,
Enholm B
,
Hytönen M
,
Arola J
,
Pajusola K
, et al.
.
Adenoviral VEGF-C overexpression induces blood vessel enlargement, tortuosity, and leakiness but no sprouting angiogenesis in the skin or mucous membranes
. FASEB J [Internet]. 2002;16(9):1041 - 9.
http://view.ncbi.nlm.nih.gov/pubmed/12087065
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Anne Saaristo et al., FASEB Journal 2002
(966.08 KB)
B
Anisimov A
,
Leppänen V-M
,
Tvorogov D
,
Zarkada G
,
Jeltsch M
,
Holopainen T
, et al.
.
The basis for the distinct biological activities of vascular endothelial growth factor receptor-1 ligands
. Sci Signal. 2013;6(282):ra52.
PubMed
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Anisimov 2013 Science Signaling
(1.92 MB)
Anisimov 2013 Science Signaling Supplement
(2.09 MB)
C
Jeltsch M
,
Jha SKumar
,
Tvorogov D
,
Anisimov A
,
Leppänen V-M
,
Holopainen T
, et al.
.
CCBE1 enhances lymphangiogenesis via ADAMTS3-mediated VEGF-C activation
. Circulation [Internet]. 2014;129(19).
http://circ.ahajournals.org/content/early/2014/02/19/CIRCULATIONAHA.113.002779.abstract
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Postprint of Jeltsch et al. 2014 (Circulation): CCBE1 enhances lymphangiogenesis via ADAMTS3-mediated VEGF-C activation
(6.6 MB)
Postprint of Jeltsch et al. 2014 (Circulation): CCBE1 enhances lymphangiogenesis via ADAMTS3-mediated VEGF-C activation (Suppl.)
(2.38 MB)
Published version of Jeltsch et al. 2014 (Circulation): CCBE1 enhances lymphangiogenesis via ADAMTS3-mediated... (incl. suppl.)
(23.21 MB)
Jeltsch M
,
Jha SKumar
,
Tvorogov D
,
Anisimov A
,
Leppänen V-M
,
Holopainen T
, et al.
.
CCBE1 enhances lymphangiogenesis via ADAMTS3-mediated VEGF-C activation
. Circulation [Internet]. 2014;129(19).
http://circ.ahajournals.org/content/early/2014/02/19/CIRCULATIONAHA.113.002779.abstract
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Postprint of Jeltsch et al. 2014 (Circulation): CCBE1 enhances lymphangiogenesis via ADAMTS3-mediated VEGF-C activation
(6.6 MB)
Postprint of Jeltsch et al. 2014 (Circulation): CCBE1 enhances lymphangiogenesis via ADAMTS3-mediated VEGF-C activation (Suppl.)
(2.38 MB)
Published version of Jeltsch et al. 2014 (Circulation): CCBE1 enhances lymphangiogenesis via ADAMTS3-mediated... (incl. suppl.)
(23.21 MB)
Krebs R
,
Tikkanen JM
,
Ropponen JO
,
Jeltsch M
,
Jokinen JJ
,
Ylä-Herttuala S
, et al.
.
Critical role of VEGF-C/VEGFR-3 signaling in innate and adaptive immune responses in experimental obliterative bronchiolitis.
Am J Pathol. 2012;181(5):1607-20.
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D
Krebs R
,
Jeltsch M
.
Die lymphangiogenic growth factors VEGF-C and VEGF-D. Part 2: The role of VEGF-C and VEGF-D in diseases of the lymphatic system. [bilingual: English, German].
Lymphologie in Forschung und Praxis [Internet]. 2013;17(2):96 - 104.
http://jeltsch.org/sites/jeltsch.org/files/JeltschMichael_Lymphforsch2013_96.pdf
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Krebs & Jeltsch (2013): The lymphangiogenic growth factors VEGF-C and VEGF-D. Part 2: The role of VEGF-C and VEGF-D in diseas...
(3.88 MB)
Krebs & Jeltsch (2013): Die lymphangiogenen Wachstumsfaktoren VEGF-C und VEGF-D. Teil 2. Die Rolle von VEGF-C und VEGF-D bei ...
(2.6 MB)
E
Tvorogov D
,
Anisimov A
,
Zheng W
,
Leppänen V-M
,
Tammela T
,
Laurinavicius S
, et al.
.
Effective suppression of vascular network formation by combination of antibodies blocking VEGFR ligand binding and receptor dimerization
. Cancer Cell [Internet]. 2010;18(6):630 - 40.
http://view.ncbi.nlm.nih.gov/pubmed/21130043
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Denis Tvorogov et al., Cancer Cell 2010
(1.3 MB)
Denis Tvorogov et al., Cancer Cell 2010, supplement
(828.69 KB)
Jha SK
,
Rauniyar K
,
Kärpänen T
,
Leppänen V-M
,
Brouillard P
,
Vikkula M
, et al.
.
Efficient activation of the lymphangiogenic growth factor VEGF-C requires the C-terminal domain of VEGF-C and the N-terminal domain of CCBE1
. Scientific Reports [Internet]. 2017;7(1):4916.
https://www.nature.com/articles/s41598-017-04982-1
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Keskitalo S
,
Tammela T
,
Lyytikka J
,
Karpanen T
,
Jeltsch M
,
Markkanen J
, et al.
.
Enhanced capillary formation stimulated by a chimeric vascular endothelial growth factor/vascular endothelial growth factor-C silk domain fusion protein
. Circ Res [Internet]. 2007;100(10):1460 - 7.
http://view.ncbi.nlm.nih.gov/pubmed/17478734
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Salla Keskitalo et al., Circulation Research 2007
(1.98 MB)
Keskitalo S
,
Tammela T
,
Lyytikka J
,
Karpanen T
,
Jeltsch M
,
Markkanen J
, et al.
.
Enhanced capillary formation stimulated by a chimeric vascular endothelial growth factor/vascular endothelial growth factor-C silk domain fusion protein
. Circ Res [Internet]. 2007;100(10):1460 - 7.
http://view.ncbi.nlm.nih.gov/pubmed/17478734
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Salla Keskitalo et al., Circulation Research 2007
(1.98 MB)
F
Kärpänen T
,
Heckman CA
,
Keskitalo S
,
Jeltsch M
,
Ollila H
,
Neufeld G
, et al.
.
Functional interaction of VEGF-C and VEGF-D with neuropilin receptors
. FASEB J [Internet]. 2006;20(9):1462 - 72.
http://view.ncbi.nlm.nih.gov/pubmed/16816121
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Terhi Kärpänen et al., FASEB Journal 2006
(2.51 MB)
Kärpänen T
,
Heckman CA
,
Keskitalo S
,
Jeltsch M
,
Ollila H
,
Neufeld G
, et al.
.
Functional interaction of VEGF-C and VEGF-D with neuropilin receptors
. FASEB J [Internet]. 2006;20(9):1462 - 72.
http://view.ncbi.nlm.nih.gov/pubmed/16816121
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Terhi Kärpänen et al., FASEB Journal 2006
(2.51 MB)
G
Chilov D
,
Kukk E
,
Taira S
,
Jeltsch M
,
Kaukonen J
,
Palotie A
, et al.
.
Genomic organization of human and mouse genes for vascular endothelial growth factor C
. J Biol Chem [Internet]. 1997;272(40):25176 - 83.
http://view.ncbi.nlm.nih.gov/pubmed/9312130
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Dmitry Chilov et al., The Journal of Biological Chemistry 1997
(517.68 KB)
Chilov D
,
Kukk E
,
Taira S
,
Jeltsch M
,
Kaukonen J
,
Palotie A
, et al.
.
Genomic organization of human and mouse genes for vascular endothelial growth factor C
. J Biol Chem [Internet]. 1997;272(40):25176 - 83.
http://view.ncbi.nlm.nih.gov/pubmed/9312130
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Dmitry Chilov et al., The Journal of Biological Chemistry 1997
(517.68 KB)
H
Jeltsch M
,
Kaipainen A
,
Joukov V
,
Meng X
,
Lakso M
,
Rauvala H
, et al.
.
Hyperplasia of lymphatic vessels in VEGF-C transgenic mice
. Science (80- ) [Internet]. 1997;276(5317):1423 - 5.
http://view.ncbi.nlm.nih.gov/pubmed/9162011
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Michael Jeltsch et al., Science 1997
(293.65 KB)
I
Heckman CA
,
Holopainen T
,
Wirzenius M
,
Keskitalo S
,
Jeltsch M
,
Wedge SR
, et al.
.
Inhibiton of VEGF-C-induced VEGFR-3 activity and lymphatic endothelial cell function by the tyrosine kinase inhibitor AZD2171
. In 98th Annual Meeting of the American-Association-for-Cancer-Research [Internet]. Los Angeles, CA: American Association for Cancer Research; 2007.
http://dx.doi.org/10.1158/0008-5472.CAN-07-5809
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Heckman et al. - 2007 - Inhibiton of VEGF-C-induced VEGFR-3 activity and l.pdf
(236.37 KB)
Hiltunen MO
,
Laitinen M
,
Turunen MP
,
Jeltsch M
,
Hartikainen J
,
Rissanen TT
, et al.
.
Intravascular adenovirus-mediated VEGF-C gene transfer reduces neointima formation in balloon-denuded rabbit aorta
. Circulation [Internet]. 2000;102(18):2262 - 8.
http://view.ncbi.nlm.nih.gov/pubmed/11056103
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Mikko Hiltunen et al., Circulation 2000
(1.44 MB)
Hiltunen MO
,
Laitinen M
,
Turunen MP
,
Jeltsch M
,
Hartikainen J
,
Rissanen TT
, et al.
.
Intravascular adenovirus-mediated VEGF-C gene transfer reduces neointima formation in balloon-denuded rabbit aorta
. Circulation [Internet]. 2000;102(18):2262 - 8.
http://view.ncbi.nlm.nih.gov/pubmed/11056103
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Mikko Hiltunen et al., Circulation 2000
(1.44 MB)
Veikkola T
,
Lohela M
,
Ikenberg K
,
Mäkinen T
,
Korff T
,
Saaristo A
, et al.
.
Intrinsic versus microenvironmental regulation of lymphatic endothelial cell phenotype and function
. FASEB J [Internet]. 2003;17(14):2006 - 13.
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Tanja Veikkola et al., FASEB Journal 2006
(598.77 KB)
Dashkevich A
,
Raissadati A
,
Syrjälä SO
,
Zarkada G
,
Keränen MAI
,
Tuuminen R
, et al.
.
Ischemia-Reperfusion Injury Enhances Lymphatic Endothelial VEGFR3 and Rejection in Cardiac Allografts
. American Journal of Transplantation [Internet]. 2015;16(4):1160-1172.
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