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Journal Article
Gerhardt H
,
Golding M
,
Fruttiger M
,
Ruhrberg C
,
Lundkvist A
,
Abramsson A
, et al.
.
VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia
. J Cell Biol [Internet]. 2003;161(6):1163 - 77.
http://view.ncbi.nlm.nih.gov/pubmed/12810700
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Holger Gerhardt et al., The Journal of Biological Chemistry 2003
(2.24 MB)
Bry M
,
Kivelä R
,
Holopainen T
,
Anisimov A
,
Tammela T
,
Soronen J
, et al.
.
Vascular endothelial growth factor-B acts as a coronary growth factor in transgenic rats without inducing angiogenesis, vascular leak, or inflammation
. Circulation [Internet]. 2010;122(17):1725 - 33.
http://view.ncbi.nlm.nih.gov/pubmed/20937974
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Maija Bry et al., Circulation 2010
(2.23 MB)
Maija Bry et al., Circulation 2010, supplement
(17.77 MB)
Bry M
,
Kivelä R
,
Holopainen T
,
Anisimov A
,
Tammela T
,
Soronen J
, et al.
.
Vascular endothelial growth factor-B acts as a coronary growth factor in transgenic rats without inducing angiogenesis, vascular leak, or inflammation
. Circulation [Internet]. 2010;122(17):1725 - 33.
http://view.ncbi.nlm.nih.gov/pubmed/20937974
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Maija Bry et al., Circulation 2010
(2.23 MB)
Maija Bry et al., Circulation 2010, supplement
(17.77 MB)
Bry M
,
Kivelä R
,
Holopainen T
,
Anisimov A
,
Tammela T
,
Soronen J
, et al.
.
Vascular endothelial growth factor-B acts as a coronary growth factor in transgenic rats without inducing angiogenesis, vascular leak, or inflammation
. Circulation [Internet]. 2010;122(17):1725 - 33.
http://view.ncbi.nlm.nih.gov/pubmed/20937974
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Maija Bry et al., Circulation 2010
(2.23 MB)
Maija Bry et al., Circulation 2010, supplement
(17.77 MB)
Bry M
,
Kivelä R
,
Holopainen T
,
Anisimov A
,
Tammela T
,
Soronen J
, et al.
.
Vascular endothelial growth factor-B acts as a coronary growth factor in transgenic rats without inducing angiogenesis, vascular leak, or inflammation
. Circulation [Internet]. 2010;122(17):1725 - 33.
http://view.ncbi.nlm.nih.gov/pubmed/20937974
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Maija Bry et al., Circulation 2010
(2.23 MB)
Maija Bry et al., Circulation 2010, supplement
(17.77 MB)
Jeltsch M
,
Karpanen T
,
Strandin T
,
Aho K
,
Lankinen H
,
Alitalo K
.
Vascular endothelial growth factor (VEGF)/VEGF-C mosaic molecules reveal specificity determinants and feature novel receptor binding patterns
. J Biol Chem [Internet]. 2006;281(17):12187 - 95.
http://view.ncbi.nlm.nih.gov/pubmed/16505489
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Michael Jeltsch et al., The Journal of Biological Chemistry 2006
(1.04 MB)
Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 1
(1.01 MB)
Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 2
(596.06 KB)
Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 3
(738.98 KB)
Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 4
(710.03 KB)
Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 5
(163.64 KB)
Achen MG
,
Jeltsch M
,
Kukk E
,
Mäkinen T
,
Vitali A
,
Wilks AF
, et al.
.
Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4)
. Proc Natl Acad Sci U S A [Internet]. 1998;95(2):548 - 53.
http://view.ncbi.nlm.nih.gov/pubmed/9435229
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Marc Achen et al., PNAS 1998
(447.59 KB)
Karkkainen MJ
,
Haiko P
,
Sainio K
,
Partanen J
,
Taipale J
,
Petrova TV
, et al.
.
Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins
. Nat Immunol [Internet]. 2004;5(1):74 - 80.
http://view.ncbi.nlm.nih.gov/pubmed/14634646
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Marika Kärkkäinen et al., Nature Immunology 2004
(3.01 MB)
Marika Kärkkäinen et al., Nature Immunology 2004, supplementary data 1
(1.27 MB)
Marika Kärkkäinen et al., Nature Immunology 2004, supplementary data 2
(1.23 MB)
Olofsson B
,
Korpelainen E
,
Pepper MS
,
Mandriota SJ
,
Aase K
,
Kumar V
, et al.
.
Vascular endothelial growth factor B (VEGF-B) binds to VEGF receptor-1 and regulates plasminogen activator activity in endothelial cells
. Proc Natl Acad Sci U S A [Internet]. 1998;95(20):11709 - 14.
http://view.ncbi.nlm.nih.gov/pubmed/9751730
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Birgitta Olofsson et al., PNAS 1998
(470.59 KB)
Albrecht I
,
Kopfstein L
,
Strittmatter K
,
Schomber T
,
Falkevall A
,
Hagberg CE
, et al.
.
Suppressive effects of vascular endothelial growth factor-B on tumor growth in a mouse model of pancreatic neuroendocrine tumorigenesis
. PLoS ONE [Internet]. 2010;5(11):e14109.
http://view.ncbi.nlm.nih.gov/pubmed/21124841
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Imke Albrecht et al., PLoS One 2010
(3.37 MB)
Albrecht I
,
Kopfstein L
,
Strittmatter K
,
Schomber T
,
Falkevall A
,
Hagberg CE
, et al.
.
Suppressive effects of vascular endothelial growth factor-B on tumor growth in a mouse model of pancreatic neuroendocrine tumorigenesis
. PLoS ONE [Internet]. 2010;5(11):e14109.
http://view.ncbi.nlm.nih.gov/pubmed/21124841
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Imke Albrecht et al., PLoS One 2010
(3.37 MB)
Leppänen V-M
,
Prota AE
,
Jeltsch M
,
Anisimov A
,
Kalkkinen N
,
Strandin T
, et al.
.
Structural determinants of growth factor binding and specificity by VEGF receptor 2
. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2010;107(6):2425 - 30.
http://view.ncbi.nlm.nih.gov/pubmed/20145116
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Veli-Matti Leppänen et al. PNAS 2010
(1 MB)
Veli-Matti Leppänen et al. PNAS 2010, supporting information
(2.23 MB)
Veikkola T
,
Jussila L
,
Makinen T
,
Karpanen T
,
Jeltsch M
,
Petrova TV
, et al.
.
Signalling via vascular endothelial growth factor receptor-3 is sufficient for lymphangiogenesis in transgenic mice
. EMBO J [Internet]. 2001;20(6):1223 - 31.
http://view.ncbi.nlm.nih.gov/pubmed/11250889
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Tanja Veikkola et al., EMBO Journal 2001
(491.14 KB)
Li X
,
Tjwa M
,
Van Hove I
,
Enholm B
,
Neven E
,
Paavonen K
, et al.
.
Reevaluation of the role of VEGF-B suggests a restricted role in the revascularization of the ischemic myocardium
. Arterioscler Thromb Vasc Biol [Internet]. 2008;28(9):1614 - 20.
http://view.ncbi.nlm.nih.gov/pubmed/18511699
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Xuri Li et al., Arteriosclerosis, Thrombosis, and Vascular Biology 2008
(738.26 KB)
Xuri Li et al., Arteriosclerosis, Thrombosis, and Vascular Biology 2008, data supplement
(1012.6 KB)
Li X
,
Tjwa M
,
Van Hove I
,
Enholm B
,
Neven E
,
Paavonen K
, et al.
.
Reevaluation of the role of VEGF-B suggests a restricted role in the revascularization of the ischemic myocardium
. Arterioscler Thromb Vasc Biol [Internet]. 2008;28(9):1614 - 20.
http://view.ncbi.nlm.nih.gov/pubmed/18511699
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Xuri Li et al., Arteriosclerosis, Thrombosis, and Vascular Biology 2008
(738.26 KB)
Xuri Li et al., Arteriosclerosis, Thrombosis, and Vascular Biology 2008, data supplement
(1012.6 KB)
Joukov V
,
Sorsa T
,
Kumar V
,
Jeltsch M
,
Claesson-Welsh L
,
Cao Y
, et al.
.
Proteolytic processing regulates receptor specificity and activity of VEGF-C
. EMBO J [Internet]. 1997;16(13):3898 - 911.
http://view.ncbi.nlm.nih.gov/pubmed/9233800
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Vladimir Joukov et al., EMBO Journal 1997
(729.21 KB)
Joukov V
,
Sorsa T
,
Kumar V
,
Jeltsch M
,
Claesson-Welsh L
,
Cao Y
, et al.
.
Proteolytic processing regulates receptor specificity and activity of VEGF-C
. EMBO J [Internet]. 1997;16(13):3898 - 911.
http://view.ncbi.nlm.nih.gov/pubmed/9233800
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Vladimir Joukov et al., EMBO Journal 1997
(729.21 KB)
Lackner M
,
Schmotz C
,
Jeltsch M
.
The Proteolytic Activation of Vascular Endothelial Growth Factor-C
. Lymphologie in Forschung und Praxis [Internet]. 2019;23(2):88 - 98.
https://doi.org/10.5281/zenodo.3629263
DOI
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English version: Lackner et al. 2019
(2.94 MB)
German version: Lackner et al. 2019
(673.37 KB)
Baluk P
,
Tammela T
,
Ator E
,
Lyubynska N
,
Achen MG
,
Hicklin DJ
, et al.
.
Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation
. J Clin Invest [Internet]. 2005;115(2):247 - 57.
http://view.ncbi.nlm.nih.gov/pubmed/15668734
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Peter Baluk et al., Journal of Clinical Investigation 2005
(1.89 MB)
Karpanen T
,
Bry M
,
Ollila HM
,
Seppänen-Laakso T
,
Liimatta E
,
Leskinen H
, et al.
.
Overexpression of vascular endothelial growth factor-B in mouse heart alters cardiac lipid metabolism and induces myocardial hypertrophy
. Circ Res [Internet]. 2008;103(9):1018 - 26.
http://view.ncbi.nlm.nih.gov/pubmed/18757827
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Terhi Kärpänen et al., Circulation Research 2008
(898.27 KB)
Terhi Kärpänen et al., Circulation Research 2008, supplement
(1.56 MB)
Gucciardo E
,
Lehti TA
,
Korhonen A
,
Salvén P
,
Lehti K
,
Jeltsch M
, et al.
.
Lymphatics and the eye. [Finnish]
. Duodecim Lääketieteellinen Aikakauskirja [Internet]. 2020;136(16):1777-1788.
https://www.duodecimlehti.fi/lehti/2020/16/duo15739
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Gucciardo et al. Lymphatics and the Eye (English version).
(3.31 MB)
Jha SKumar
,
Rauniyar K
,
Chronowska E
,
Mattonet K
,
Maina EWairimu
,
Koistinen H
, et al.
.
KLK3/PSA and cathepsin D activate VEGF-C and VEGF-D
. eLife [Internet]. 2019;8:e44478.
https://elifesciences.org/articles/44478
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Jha & Rauniyar et al. 2019
(3.84 MB)
Veikkola T
,
Lohela M
,
Ikenberg K
,
Mäkinen T
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Korff T
,
Saaristo A
, et al.
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Intrinsic versus microenvironmental regulation of lymphatic endothelial cell phenotype and function
. FASEB J [Internet]. 2003;17(14):2006 - 13.
http://view.ncbi.nlm.nih.gov/pubmed/14597670
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Tanja Veikkola et al., FASEB Journal 2006
(598.77 KB)
Jeltsch M
,
Kaipainen A
,
Joukov V
,
Meng X
,
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,
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, et al.
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Hyperplasia of lymphatic vessels in VEGF-C transgenic mice
. Science (80- ) [Internet]. 1997;276(5317):1423 - 5.
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Michael Jeltsch et al., Science 1997
(293.65 KB)
Saharinen P
,
Helotera H
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Miettinen J
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Norrmen C
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Claudin-like protein 24 interacts with the VEGFR-2 and VEGFR-3 pathways and regulates lymphatic vessel development
. Genes Dev [Internet]. 2010;24(9):875 - 80.
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Pipsa Saharinen et al., Genes & Development 2010
(1.2 MB)
Pipsa Saharinen et al., Genes & Development 2010, supplement
(9.15 MB)
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