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. Signalling via VEGFR-3 is sufficient for lymphangiogenesis in transgenic mice. Teoksessa Molecular Targets and Cancer Therapeutics: Discovery, Biology, and Clinical Applications. Miami Beach, Florida; 2001. 
Jussila et al., 2001 (279.47 KB)
Jussila et al., 2001 (279.47 KB). Adenoviral VEGF-C overexpression induces blood vessel enlargement, tortuosity, and leakiness but no sprouting angiogenesis in the skin or mucous membranes. FASEB J [Internet]. 2002;16(9):1041 - 9. http://view.ncbi.nlm.nih.gov/pubmed/12087065 Anne Saaristo et al., FASEB Journal 2002 (966.08 KB)
Anne Saaristo et al., FASEB Journal 2002 (966.08 KB). Distinct architecture of lymphatic vessels induced by chimeric vascular endothelial growth factor-C/vascular endothelial growth factor heparin-binding domain fusion proteins. Circ Res [Internet]. 2007;100(10):1468 - 75. http://view.ncbi.nlm.nih.gov/pubmed/17478733 Tuomas Tammela et al., Circulation Research 2007 (1.1 MB)
Tuomas Tammela et al., Circulation Research 2007 (1.1 MB). Effective suppression of vascular network formation by combination of antibodies blocking VEGFR ligand binding and receptor dimerization. Cancer Cell [Internet]. 2010;18(6):630 - 40. http://view.ncbi.nlm.nih.gov/pubmed/21130043 Denis Tvorogov et al., Cancer Cell 2010 (1.3 MB) Denis Tvorogov et al., Cancer Cell 2010, supplement (828.69 KB)
Denis Tvorogov et al., Cancer Cell 2010 (1.3 MB) Denis Tvorogov et al., Cancer Cell 2010, supplement (828.69 KB). Effective suppression of vascular network formation by combination of antibodies blocking VEGFR ligand binding and receptor dimerization. Cancer Cell [Internet]. 2010;18(6):630 - 40. http://view.ncbi.nlm.nih.gov/pubmed/21130043 Denis Tvorogov et al., Cancer Cell 2010 (1.3 MB) Denis Tvorogov et al., Cancer Cell 2010, supplement (828.69 KB)
Denis Tvorogov et al., Cancer Cell 2010 (1.3 MB) Denis Tvorogov et al., Cancer Cell 2010, supplement (828.69 KB). Enhanced capillary formation stimulated by a chimeric vascular endothelial growth factor/vascular endothelial growth factor-C silk domain fusion protein. Circ Res [Internet]. 2007;100(10):1460 - 7. http://view.ncbi.nlm.nih.gov/pubmed/17478734 Salla Keskitalo et al., Circulation Research 2007 (1.98 MB)
Salla Keskitalo et al., Circulation Research 2007 (1.98 MB). Functional interaction of VEGF-C and VEGF-D with neuropilin receptors. FASEB J [Internet]. 2006;20(9):1462 - 72. http://view.ncbi.nlm.nih.gov/pubmed/16816121 Terhi Kärpänen et al., FASEB Journal 2006 (2.51 MB)
Terhi Kärpänen et al., FASEB Journal 2006 (2.51 MB). Genesis and pathogenesis of lymphatic vessels. Cell Tissue Res [Internet]. 2003;314(1):69 - 84. http://view.ncbi.nlm.nih.gov/pubmed/12942362 Michael Jeltsch et al., Cell and Tissue Research 2003 (562.33 KB)
Michael Jeltsch et al., Cell and Tissue Research 2003 (562.33 KB). Genomic organization of human and mouse genes for vascular endothelial growth factor C. J Biol Chem [Internet]. 1997;272(40):25176 - 83. http://view.ncbi.nlm.nih.gov/pubmed/9312130 Dmitry Chilov et al., The Journal of Biological Chemistry 1997 (517.68 KB)
Dmitry Chilov et al., The Journal of Biological Chemistry 1997 (517.68 KB). Intravascular adenovirus-mediated VEGF-C gene transfer reduces neointima formation in balloon-denuded rabbit aorta. Circulation [Internet]. 2000;102(18):2262 - 8. http://view.ncbi.nlm.nih.gov/pubmed/11056103 Mikko Hiltunen et al., Circulation 2000 (1.44 MB)
Mikko Hiltunen et al., Circulation 2000 (1.44 MB). Intravascular adenovirus-mediated VEGF-C gene transfer reduces neointima formation in balloon-denuded rabbit aorta. Circulation [Internet]. 2000;102(18):2262 - 8. http://view.ncbi.nlm.nih.gov/pubmed/11056103 Mikko Hiltunen et al., Circulation 2000 (1.44 MB)
Mikko Hiltunen et al., Circulation 2000 (1.44 MB). Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation. J Clin Invest [Internet]. 2005;115(2):247 - 57. http://view.ncbi.nlm.nih.gov/pubmed/15668734 Peter Baluk et al., Journal of Clinical Investigation 2005 (1.89 MB)
Peter Baluk et al., Journal of Clinical Investigation 2005 (1.89 MB). Reevaluation of the role of VEGF-B suggests a restricted role in the revascularization of the ischemic myocardium. Arterioscler Thromb Vasc Biol [Internet]. 2008;28(9):1614 - 20. http://view.ncbi.nlm.nih.gov/pubmed/18511699 Xuri Li et al., Arteriosclerosis, Thrombosis, and Vascular Biology 2008 (738.26 KB) Xuri Li et al., Arteriosclerosis, Thrombosis, and Vascular Biology 2008, data supplement (1012.6 KB)
Xuri Li et al., Arteriosclerosis, Thrombosis, and Vascular Biology 2008 (738.26 KB) Xuri Li et al., Arteriosclerosis, Thrombosis, and Vascular Biology 2008, data supplement (1012.6 KB). Signalling via vascular endothelial growth factor receptor-3 is sufficient for lymphangiogenesis in transgenic mice. EMBO J [Internet]. 2001;20(6):1223 - 31. http://view.ncbi.nlm.nih.gov/pubmed/11250889 Tanja Veikkola et al., EMBO Journal 2001 (491.14 KB)
Tanja Veikkola et al., EMBO Journal 2001 (491.14 KB). Structural determinants of vascular endothelial growth factor-D receptor binding and specificity. Blood [Internet]. 2011;117(5):1507 - 15. http://view.ncbi.nlm.nih.gov/pubmed/21148085 Veli-Matti Leppänen & Michael Jeltsch et al., Blood 2011 (1.17 MB) Veli-Matti Leppänen & Michael Jeltsch et al. Blood 2011, supplementary data (342.97 KB)
Veli-Matti Leppänen & Michael Jeltsch et al., Blood 2011 (1.17 MB) Veli-Matti Leppänen & Michael Jeltsch et al. Blood 2011, supplementary data (342.97 KB). Structural determinants of vascular endothelial growth factor-D receptor binding and specificity. Blood [Internet]. 2011;117(5):1507 - 15. http://view.ncbi.nlm.nih.gov/pubmed/21148085 Veli-Matti Leppänen & Michael Jeltsch et al., Blood 2011 (1.17 MB) Veli-Matti Leppänen & Michael Jeltsch et al. Blood 2011, supplementary data (342.97 KB)
Veli-Matti Leppänen & Michael Jeltsch et al., Blood 2011 (1.17 MB) Veli-Matti Leppänen & Michael Jeltsch et al. Blood 2011, supplementary data (342.97 KB). Vascular endothelial cell growth factor receptor 3-mediated activation of lymphatic endothelium is crucial for tumor cell entry and spread via lymphatic vessels. Cancer Res [Internet]. 2005;65(11):4739 - 46. http://view.ncbi.nlm.nih.gov/pubmed/15930292 Yulong He et al., Cancer Research 2005 (1.82 MB)
Yulong He et al., Cancer Research 2005 (1.82 MB). Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins. Nat Immunol [Internet]. 2004;5(1):74 - 80. http://view.ncbi.nlm.nih.gov/pubmed/14634646 Marika Kärkkäinen et al., Nature Immunology 2004 (3.01 MB) Marika Kärkkäinen et al., Nature Immunology 2004, supplementary data 1 (1.27 MB) Marika Kärkkäinen et al., Nature Immunology 2004, supplementary data 2 (1.23 MB)
Marika Kärkkäinen et al., Nature Immunology 2004 (3.01 MB) Marika Kärkkäinen et al., Nature Immunology 2004, supplementary data 1 (1.27 MB) Marika Kärkkäinen et al., Nature Immunology 2004, supplementary data 2 (1.23 MB). Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins. Nat Immunol [Internet]. 2004;5(1):74 - 80. http://view.ncbi.nlm.nih.gov/pubmed/14634646 Marika Kärkkäinen et al., Nature Immunology 2004 (3.01 MB) Marika Kärkkäinen et al., Nature Immunology 2004, supplementary data 1 (1.27 MB) Marika Kärkkäinen et al., Nature Immunology 2004, supplementary data 2 (1.23 MB)
Marika Kärkkäinen et al., Nature Immunology 2004 (3.01 MB) Marika Kärkkäinen et al., Nature Immunology 2004, supplementary data 1 (1.27 MB) Marika Kärkkäinen et al., Nature Immunology 2004, supplementary data 2 (1.23 MB). Vascular endothelial growth factor-B acts as a coronary growth factor in transgenic rats without inducing angiogenesis, vascular leak, or inflammation. Circulation [Internet]. 2010;122(17):1725 - 33. http://view.ncbi.nlm.nih.gov/pubmed/20937974 Maija Bry et al., Circulation 2010 (2.23 MB) Maija Bry et al., Circulation 2010, supplement (17.77 MB)
Maija Bry et al., Circulation 2010 (2.23 MB) Maija Bry et al., Circulation 2010, supplement (17.77 MB). VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development. Development [Internet]. 1996;122(12):3829 - 37. http://view.ncbi.nlm.nih.gov/pubmed/9012504 Eola Kukk et al., Development 1996 (805.94 KB)
Eola Kukk et al., Development 1996 (805.94 KB). VEGF-C/VEGFR-3 Signaling Regulates Inflammatory Response in Development of Obliterative Airway Disease. Journal of Heart and Lung Transplantation. 2011;30:S118 - S118.