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K
Krebs R, Jeltsch M. The lymphangiogenic growth factors VEGF-C and VEGF-D. Part 1: Basic principles and embryonic development. [bilingual: English, German]. Lymphologie in Forschung und Praxis [Internet]. 2013;17(1):30 - 37. http://jeltsch.org/sites/jeltsch.org/files/JeltschMichael_Lymphforsch2013_30.pdfPDF ikon Krebs & Jeltsch (2013): The lymphangiogenic growth factors VEGF-C and VEGF-D. Part 1: Fundamentals and embryonic development. (2.08 MB)PDF ikon Krebs & Jeltsch (2013): Die lymphangiogenen Wachstumsfaktoren VEGF-C und VEGF-D. Teil 1. Grundlagen und Embryonalentwicklung. (1.82 MB)
Koistinen H, Künnapuu J, Jeltsch M. KLK3 in the Regulation of Angiogenesis—Tumorigenic or Not?. International Journal of Molecular Sciences [Internet]. 2021;22(24):13545. https://www.mdpi.com/1422-0067/22/24/13545PDF ikon Koistinen et al. - 2021 - KLK3 in the Regulation of Angiogenesis—Tumorigenic or Not? (1.28 MB)
Keskitalo S, Tammela T, Lyytikka J, Karpanen T, Jeltsch M, Markkanen J, et al.. Enhanced capillary formation stimulated by a chimeric vascular endothelial growth factor/vascular endothelial growth factor-C silk domain fusion protein. Circ Res [Internet]. 2007;100(10):1460 - 7. http://view.ncbi.nlm.nih.gov/pubmed/17478734PDF ikon Salla Keskitalo et al., Circulation Research 2007 (1.98 MB)
Karpanen T, Bry M, Ollila HM, Seppänen-Laakso T, Liimatta E, Leskinen H, et al.. Overexpression of vascular endothelial growth factor-B in mouse heart alters cardiac lipid metabolism and induces myocardial hypertrophy. Circ Res [Internet]. 2008;103(9):1018 - 26. http://view.ncbi.nlm.nih.gov/pubmed/18757827PDF ikon Terhi Kärpänen et al., Circulation Research 2008 (898.27 KB)PDF ikon Terhi Kärpänen et al., Circulation Research 2008, supplement (1.56 MB)
Kärpänen T, Heckman CA, Keskitalo S, Jeltsch M, Ollila H, Neufeld G, et al.. Functional interaction of VEGF-C and VEGF-D with neuropilin receptors. FASEB J [Internet]. 2006;20(9):1462 - 72. http://view.ncbi.nlm.nih.gov/pubmed/16816121PDF ikon Terhi Kärpänen et al., FASEB Journal 2006 (2.51 MB)
Karkkainen MJ, Haiko P, Sainio K, Partanen J, Taipale J, Petrova TV, et al.. Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins. Nat Immunol [Internet]. 2004;5(1):74 - 80. http://view.ncbi.nlm.nih.gov/pubmed/14634646PDF ikon Marika Kärkkäinen et al., Nature Immunology 2004 (3.01 MB)PDF ikon Marika Kärkkäinen et al., Nature Immunology 2004, supplementary data 1 (1.27 MB)PDF ikon Marika Kärkkäinen et al., Nature Immunology 2004, supplementary data 2 (1.23 MB)
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Jussila L, Veikkola T, Jeltsch M, Thurston G, McDonald D, Achen M, et al.. Signalling via VEGFR-3 is sufficient for lymphangiogenesis in transgenic mice. In Molecular Targets and Cancer Therapeutics: Discovery, Biology, and Clinical Applications. Miami Beach, Florida; 2001. PDF ikon Jussila et al., 2001 (279.47 KB)
Joukov V, Sorsa T, Kumar V, Jeltsch M, Claesson-Welsh L, Cao Y, et al.. Proteolytic processing regulates receptor specificity and activity of VEGF-C. EMBO J [Internet]. 1997;16(13):3898 - 911. http://view.ncbi.nlm.nih.gov/pubmed/9233800PDF ikon Vladimir Joukov et al., EMBO Journal 1997 (729.21 KB)
Joukov V, Kaipainen A, Jeltsch M, Pajusola K, Olofsson B, Kumar V, et al.. Vascular endothelial growth factors VEGF-B and VEGF-C. J Cell Physiol [Internet]. 1997;173(2):211 - 5. http://view.ncbi.nlm.nih.gov/pubmed/9365524PDF ikon Vladimir Joukov et al., Journal of Cellular Physiology 1997 (127.57 KB)
Jha SK, Rauniyar K, Chronowska E, Mattonet K, Maina EW, Koistinen H, et al.. KLK3/PSA and cathepsin D activate VEGF-C and VEGF-D. eLife [Internet]. 2019;8:e44478. https://elifesciences.org/articles/44478PDF ikon Jha & Rauniyar et al. 2019 (3.84 MB)
Jha SK. Mechanism of VEGF-C Activation and Effect on Lymphatic Vessel Growth and Regeneration [Internet]. [Helsinki, Finland]: University of Helsinki; 2020. https://helda.helsinki.fi/handle/10138/314714PDF ikon Jha - 2020 - Mechanism of VEGF-C Activation and Effect on Lymphatic Vessel Growth and Regeneration (1.96 MB)
Jeltsch M, Kaipainen A, Joukov V, Meng X, Lakso M, Rauvala H, et al.. Hyperplasia of lymphatic vessels in VEGF-C transgenic mice. Science (80- ) [Internet]. 1997;276(5317):1423 - 5. http://view.ncbi.nlm.nih.gov/pubmed/9162011PDF ikon Michael Jeltsch et al., Science 1997 (293.65 KB)
Jeltsch M. VEGFR-3 Ligands and Lymphangiogenesis [Internet]. University of Helsinki. 2002. http://ethesis.helsinki.fi/julkaisut/mat/bioti/vk/jeltschPDF ikon Michael Jeltsch, PhD Thesis, 2002 (1.75 MB)
Jeltsch M, Karpanen T, Strandin T, Aho K, Lankinen H, Alitalo K. Vascular endothelial growth factor (VEGF)/VEGF-C mosaic molecules reveal specificity determinants and feature novel receptor binding patterns. J Biol Chem [Internet]. 2006;281(17):12187 - 95. http://view.ncbi.nlm.nih.gov/pubmed/16505489PDF ikon Michael Jeltsch et al., The Journal of Biological Chemistry 2006 (1.04 MB)PDF ikon Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 1 (1.01 MB)PDF ikon Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 2 (596.06 KB)PDF ikon Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 3 (738.98 KB)PDF ikon Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 4 (710.03 KB)PDF ikon Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 5 (163.64 KB)
Jeltsch M. Drug-induced lymphangiogenesis. In 3. Schweizer Lymphsymposium [Internet]. Juzo; 2021. https://doi.org/10.5281/zenodo.6034307PDF ikon Jeltsch - 2021 - Drug-induced lymphangiogenesis (1.9 MB)
Jeltsch M. What you should know about VEGF-C when working with lymphatics [German]. In Lymphologie 2017 [Internet]. Bad Soden (Frankfurt), Germany; 2017. https://jeltsch.org/Abstrakt-BadSoden2017PDF ikon Extended Abstract (published in Vasomed, 2018) (226.5 KB)
Jeltsch M, Alitalo K. Lymphatic-to-blood vessel transdifferentiation in zebrafish. Nature Cardiovascular Research [Internet]. 2022;1(6):539 - 541. https://rdcu.be/cOjJ0
Jeltsch M, Tammela T, Alitalo K, Wilting J. Genesis and pathogenesis of lymphatic vessels. Cell Tissue Res [Internet]. 2003;314(1):69 - 84. http://view.ncbi.nlm.nih.gov/pubmed/12942362PDF ikon Michael Jeltsch et al., Cell and Tissue Research 2003 (562.33 KB)
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Hiltunen MO, Laitinen M, Turunen MP, Jeltsch M, Hartikainen J, Rissanen TT, et al.. Intravascular adenovirus-mediated VEGF-C gene transfer reduces neointima formation in balloon-denuded rabbit aorta. Circulation [Internet]. 2000;102(18):2262 - 8. http://view.ncbi.nlm.nih.gov/pubmed/11056103PDF ikon Mikko Hiltunen et al., Circulation 2000 (1.44 MB)
Heckman CA, Holopainen T, Wirzenius M, Keskitalo S, Jeltsch M, Ylä-Herttuala S, et al.. The tyrosine kinase inhibitor cediranib blocks ligand-induced vascular endothelial growth factor receptor-3 activity and lymphangiogenesis. Cancer Res [Internet]. 2008;68(12):4754 - 62. http://view.ncbi.nlm.nih.gov/pubmed/18559522PDF ikon Caroline Heckman et al., Cancer Research 2008 (504.8 KB)
He Y, Rajantie I, Pajusola K, Jeltsch M, Holopainen T, Yla-Herttuala S, et al.. Vascular endothelial cell growth factor receptor 3-mediated activation of lymphatic endothelium is crucial for tumor cell entry and spread via lymphatic vessels. Cancer Res [Internet]. 2005;65(11):4739 - 46. http://view.ncbi.nlm.nih.gov/pubmed/15930292PDF ikon Yulong He et al., Cancer Research 2005 (1.82 MB)
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Gucciardo E, Lehti TA, Korhonen A, Salvén P, Lehti K, Jeltsch M, et al.. Lymphatics and the eye. [Finnish]. Duodecim Lääketieteellinen Aikakauskirja [Internet]. 2020;136(16):1777-1788. https://www.duodecimlehti.fi/lehti/2020/16/duo15739PDF ikon Gucciardo et al. Lymphatics and the Eye (English version). (3.31 MB)
Gerhardt H, Golding M, Fruttiger M, Ruhrberg C, Lundkvist A, Abramsson A, et al.. VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia. J Cell Biol [Internet]. 2003;161(6):1163 - 77. http://view.ncbi.nlm.nih.gov/pubmed/12810700PDF ikon Holger Gerhardt et al., The Journal of Biological Chemistry 2003 (2.24 MB)
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Enholm B, Karpanen T, Jeltsch M, Kubo H, Stenback F, Prevo R, et al.. Adenoviral expression of vascular endothelial growth factor-C induces lymphangiogenesis in the skin. Circ Res [Internet]. 2001;88(6):623 - 9. http://view.ncbi.nlm.nih.gov/pubmed/11282897PDF ikon Bernd Enholm et al., Circulation Research 2001 (2.93 MB)
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Chilov D, Kukk E, Taira S, Jeltsch M, Kaukonen J, Palotie A, et al.. Genomic organization of human and mouse genes for vascular endothelial growth factor C. J Biol Chem [Internet]. 1997;272(40):25176 - 83. http://view.ncbi.nlm.nih.gov/pubmed/9312130PDF ikon Dmitry Chilov et al., The Journal of Biological Chemistry 1997  (517.68 KB)

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