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Jeltsch M
.
Lymphangiogenesis in Health and Disease
[Internet]. 41st European Societry of Lymphology (ESL) Congress. Lausanne, Switzerland: European Group of Lymphology; 2015.
http://www.eurolymphology.org/JOURNAL/VOL26-N72-2015/#p=10
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Abstract of the Presentation (Michael Jeltsch)
(75.34 KB)
K
Jha SKumar
,
Rauniyar K
,
Chronowska E
,
Mattonet K
,
Maina EWairimu
,
Koistinen H
, et al.
.
KLK3/PSA and cathepsin D activate VEGF-C and VEGF-D
. eLife [Internet]. 2019;8:e44478.
https://elifesciences.org/articles/44478
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Jha & Rauniyar et al. 2019
(3.84 MB)
I
Mukenge S
,
Jha SK
,
Catena M
,
Manara E
,
Leppänen V‐M
,
Lenti E
, et al.
.
Investigation on the role of biallelic variants in VEGF‐C found in a patient affected by Milroy‐like lymphedema
. Molecular Genetics & Genomic Medicine [Internet]. 2020;00:e1389.
https://onlinelibrary.wiley.com/doi/abs/10.1002/mgg3.1389
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Mukenge et al. 2020
(1.06 MB)
Veikkola T
,
Lohela M
,
Ikenberg K
,
Mäkinen T
,
Korff T
,
Saaristo A
, et al.
.
Intrinsic versus microenvironmental regulation of lymphatic endothelial cell phenotype and function
. FASEB J [Internet]. 2003;17(14):2006 - 13.
http://view.ncbi.nlm.nih.gov/pubmed/14597670
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Tanja Veikkola et al., FASEB Journal 2006
(598.77 KB)
Heckman CA
,
Holopainen T
,
Wirzenius M
,
Keskitalo S
,
Jeltsch M
,
Wedge SR
, et al.
.
Inhibiton of VEGF-C-induced VEGFR-3 activity and lymphatic endothelial cell function by the tyrosine kinase inhibitor AZD2171
. In 98th Annual Meeting of the American-Association-for-Cancer-Research [Internet]. Los Angeles, CA: American Association for Cancer Research; 2007.
http://dx.doi.org/10.1158/0008-5472.CAN-07-5809
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Heckman et al. - 2007 - Inhibiton of VEGF-C-induced VEGFR-3 activity and l.pdf
(236.37 KB)
H
Mattonet K
,
Jeltsch M
.
Heterogeneity of the origin of the lymphatic system. [German].
Lymphologie in Forschung und Praxis [Internet]. 2015;19(2):84-88.
http://www.dglymph.de/fileadmin/global/pdfs/LymphForsch_2-15.pdf
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Mattonet & Jeltsch 2015: Heterogeneity of the origin of the lymphatic system.
(3.58 MB)
Mattonet & Jeltsch 2015: Über die heterogene Herkunft des Lymphgefäßsystems.
(288.77 KB)
G
Mattonet K
,
Wilting J
,
Jeltsch M
.
The genetic causes of primary lymphedema.
In:
Weissleder H
,
Schuchhardt C
. Erkrankungen des Lymphgefäßsystems. 6th ed. Cologne: Viavital Verlag; 2015. pp. 210-229.
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Mattonet et al. 2015: The genetic causes of primary lymphedema. [English]
(3.8 MB)
Mattonet et al. 2015: The genetic causes of primary lymphedema. [German]
(676.52 KB)
Jeltsch M
,
Tammela T
,
Alitalo K
,
Wilting J
.
Genesis and pathogenesis of lymphatic vessels
. Cell Tissue Res [Internet]. 2003;314(1):69 - 84.
http://view.ncbi.nlm.nih.gov/pubmed/12942362
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Michael Jeltsch et al., Cell and Tissue Research 2003
(562.33 KB)
F
Kärpänen T
,
Heckman CA
,
Keskitalo S
,
Jeltsch M
,
Ollila H
,
Neufeld G
, et al.
.
Functional interaction of VEGF-C and VEGF-D with neuropilin receptors
. FASEB J [Internet]. 2006;20(9):1462 - 72.
http://view.ncbi.nlm.nih.gov/pubmed/16816121
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Terhi Kärpänen et al., FASEB Journal 2006
(2.51 MB)
Johns SC
,
Yin X
,
Jeltsch M
,
Bishop JR
,
Schuksz M
,
Ghazal REl
, et al.
.
Functional Importance of a Proteoglycan Co-Receptor in Pathologic Lymphangiogenesis
. Circulation Research [Internet]. 2016;119(2):210-221.
http://circres.ahajournals.org/content/early/2016/05/25/CIRCRESAHA.116.308504
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Johns et al. 2016: Functional Importance of a Proteoglycan Co-Receptor in Pathologic Lymphangiogenesis
(3.69 MB)
Johns et al. 2016: Functional Importance of a Proteoglycan Co-Receptor in Pathologic Lymphangiogenesis: Supplemental Data
(3.3 MB)
M Roukens G
,
Peterson-Maduro J
,
Padberg Y
,
Jeltsch M
,
Leppänen V-M
,
Bos FL
, et al.
.
Functional Dissection of the CCBE1 Protein: A Crucial Requirement for the Collagen Repeat Domain.
Circ Res [Internet]. 2015;116(10):1660-1669.
http://circres.ahajournals.org/content/116/10/1660.long
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Jeltsch M
.
Functional Analysis of VEGF-B and VEGF-C
[Internet]. University of Helsinki. [Helsinki]: Univeristy of Helsinki; 1997.
http://urn.fi/URN:NBN:fi-fe977347
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Michael Jeltsch, MSc Thesis, 1997
(3.12 MB)
Jeltsch M
.
From Molecular Genetics and Biology to Effective Treatments of Lymphatic Disorders
[Internet]. 42nd Congress of the European Society of Lymphology. Mulhouse, France; 2016.
http://www.eurolymphology.org/JOURNAL/VOL28-N74-2016/#p=14
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Jeltsch 2016: From Molecular Genetics and Biology to Effective Treatments of Lymphatic Disorders
(683.85 KB)
Batchu KChaithanya
,
Hänninen S
,
Jha SKumar
,
Jeltsch M
,
Somerharju P
.
Factors regulating the substrate specificity of cytosolic phospholipase A2-alpha in vitro
. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 2016;1861(11):1597.
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Batchu et al. - 2016 - Factors regulating the substrate specificity of cy.pdf
(986.25 KB)
E
Keskitalo S
,
Tammela T
,
Lyytikka J
,
Karpanen T
,
Jeltsch M
,
Markkanen J
, et al.
.
Enhanced capillary formation stimulated by a chimeric vascular endothelial growth factor/vascular endothelial growth factor-C silk domain fusion protein
. Circ Res [Internet]. 2007;100(10):1460 - 7.
http://view.ncbi.nlm.nih.gov/pubmed/17478734
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Salla Keskitalo et al., Circulation Research 2007
(1.98 MB)
Jha SK
,
Rauniyar K
,
Kärpänen T
,
Leppänen V-M
,
Brouillard P
,
Vikkula M
, et al.
.
Efficient activation of the lymphangiogenic growth factor VEGF-C requires the C-terminal domain of VEGF-C and the N-terminal domain of CCBE1
. Scientific Reports [Internet]. 2017;7(1):4916.
https://www.nature.com/articles/s41598-017-04982-1
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Tvorogov D
,
Anisimov A
,
Zheng W
,
Leppänen V-M
,
Tammela T
,
Laurinavicius S
, et al.
.
Effective suppression of vascular network formation by combination of antibodies blocking VEGFR ligand binding and receptor dimerization
. Cancer Cell [Internet]. 2010;18(6):630 - 40.
http://view.ncbi.nlm.nih.gov/pubmed/21130043
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Denis Tvorogov et al., Cancer Cell 2010
(1.3 MB)
Denis Tvorogov et al., Cancer Cell 2010, supplement
(828.69 KB)
D
Tammela T
,
He Y
,
Lyytikkä J
,
Jeltsch M
,
Markkanen J
,
Pajusola K
, et al.
.
Distinct architecture of lymphatic vessels induced by chimeric vascular endothelial growth factor-C/vascular endothelial growth factor heparin-binding domain fusion proteins
. Circ Res [Internet]. 2007;100(10):1468 - 75.
http://view.ncbi.nlm.nih.gov/pubmed/17478733
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Tuomas Tammela et al., Circulation Research 2007
(1.1 MB)
Krebs R
,
Jeltsch M
.
Die lymphangiogenic growth factors VEGF-C and VEGF-D. Part 2: The role of VEGF-C and VEGF-D in diseases of the lymphatic system. [bilingual: English, German].
Lymphologie in Forschung und Praxis [Internet]. 2013;17(2):96 - 104.
http://jeltsch.org/sites/jeltsch.org/files/JeltschMichael_Lymphforsch2013_96.pdf
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Krebs & Jeltsch (2013): The lymphangiogenic growth factors VEGF-C and VEGF-D. Part 2: The role of VEGF-C and VEGF-D in diseas...
(3.88 MB)
Krebs & Jeltsch (2013): Die lymphangiogenen Wachstumsfaktoren VEGF-C und VEGF-D. Teil 2. Die Rolle von VEGF-C und VEGF-D bei ...
(2.6 MB)
Die lymphangiogenen Wachstumsfaktoren VEGF-C und VEGF-D
. Lymphologie in Forschung und Praxis. 2013;17(1):30-37.
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C
Krebs R
,
Tikkanen JM
,
Ropponen JO
,
Jeltsch M
,
Jokinen JJ
,
Ylä-Herttuala S
, et al.
.
Critical role of VEGF-C/VEGFR-3 signaling in innate and adaptive immune responses in experimental obliterative bronchiolitis.
Am J Pathol. 2012;181(5):1607-20.
PubMed
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Saharinen P
,
Helotera H
,
Miettinen J
,
Norrmen C
,
D'Amico G
,
Jeltsch M
, et al.
.
Claudin-like protein 24 interacts with the VEGFR-2 and VEGFR-3 pathways and regulates lymphatic vessel development
. Genes Dev [Internet]. 2010;24(9):875 - 80.
http://view.ncbi.nlm.nih.gov/pubmed/20439428
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Pipsa Saharinen et al., Genes & Development 2010
(1.2 MB)
Pipsa Saharinen et al., Genes & Development 2010, supplement
(9.15 MB)
Jeltsch M
,
Jha SKumar
,
Tvorogov D
,
Anisimov A
,
Leppänen V-M
,
Holopainen T
, et al.
.
CCBE1 enhances lymphangiogenesis via ADAMTS3-mediated VEGF-C activation
. Circulation [Internet]. 2014;129(19).
http://circ.ahajournals.org/content/early/2014/02/19/CIRCULATIONAHA.113.002779.abstract
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Postprint of Jeltsch et al. 2014 (Circulation): CCBE1 enhances lymphangiogenesis via ADAMTS3-mediated VEGF-C activation
(6.6 MB)
Postprint of Jeltsch et al. 2014 (Circulation): CCBE1 enhances lymphangiogenesis via ADAMTS3-mediated VEGF-C activation (Suppl.)
(2.38 MB)
Published version of Jeltsch et al. 2014 (Circulation): CCBE1 enhances lymphangiogenesis via ADAMTS3-mediated... (incl. suppl.)
(23.21 MB)
B
Anisimov A
,
Leppänen V-M
,
Tvorogov D
,
Zarkada G
,
Jeltsch M
,
Holopainen T
, et al.
.
The basis for the distinct biological activities of vascular endothelial growth factor receptor-1 ligands
. Sci Signal. 2013;6(282):ra52.
PubMed
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Anisimov 2013 Science Signaling
(1.92 MB)
Anisimov 2013 Science Signaling Supplement
(2.09 MB)
A
Saaristo A
,
Veikkola T
,
Enholm B
,
Hytönen M
,
Arola J
,
Pajusola K
, et al.
.
Adenoviral VEGF-C overexpression induces blood vessel enlargement, tortuosity, and leakiness but no sprouting angiogenesis in the skin or mucous membranes
. FASEB J [Internet]. 2002;16(9):1041 - 9.
http://view.ncbi.nlm.nih.gov/pubmed/12087065
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Anne Saaristo et al., FASEB Journal 2002
(966.08 KB)
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