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Functional Analysis of VEGF-B and VEGF-C [Internet]. University of Helsinki. [Helsinki]: Univeristy of Helsinki; 1997. http://urn.fi/URN:NBN:fi-fe977347
Michael Jeltsch, MSc Thesis, 1997 (3.12 MB)
Michael Jeltsch, MSc Thesis, 1997 (3.12 MB). Adenoviral VEGF-C overexpression induces blood vessel enlargement, tortuosity, and leakiness but no sprouting angiogenesis in the skin or mucous membranes. FASEB J [Internet]. 2002;16(9):1041 - 9. http://view.ncbi.nlm.nih.gov/pubmed/12087065 Anne Saaristo et al., FASEB Journal 2002 (966.08 KB)
Anne Saaristo et al., FASEB Journal 2002 (966.08 KB). VEGFR-3 Ligands and Lymphangiogenesis [Internet]. University of Helsinki. 2002. http://ethesis.helsinki.fi/julkaisut/mat/bioti/vk/jeltsch Michael Jeltsch, PhD Thesis, 2002 (1.75 MB)
Michael Jeltsch, PhD Thesis, 2002 (1.75 MB). Genesis and pathogenesis of lymphatic vessels. Cell Tissue Res [Internet]. 2003;314(1):69 - 84. http://view.ncbi.nlm.nih.gov/pubmed/12942362 Michael Jeltsch et al., Cell and Tissue Research 2003 (562.33 KB)
Michael Jeltsch et al., Cell and Tissue Research 2003 (562.33 KB). Intrinsic versus microenvironmental regulation of lymphatic endothelial cell phenotype and function. FASEB J [Internet]. 2003;17(14):2006 - 13. http://view.ncbi.nlm.nih.gov/pubmed/14597670 Tanja Veikkola et al., FASEB Journal 2006 (598.77 KB)
Tanja Veikkola et al., FASEB Journal 2006 (598.77 KB). VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia. J Cell Biol [Internet]. 2003;161(6):1163 - 77. http://view.ncbi.nlm.nih.gov/pubmed/12810700 Holger Gerhardt et al., The Journal of Biological Chemistry 2003 (2.24 MB)
Holger Gerhardt et al., The Journal of Biological Chemistry 2003 (2.24 MB). Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins. Nat Immunol [Internet]. 2004;5(1):74 - 80. http://view.ncbi.nlm.nih.gov/pubmed/14634646 Marika Kärkkäinen et al., Nature Immunology 2004 (3.01 MB) Marika Kärkkäinen et al., Nature Immunology 2004, supplementary data 1 (1.27 MB) Marika Kärkkäinen et al., Nature Immunology 2004, supplementary data 2 (1.23 MB)
Marika Kärkkäinen et al., Nature Immunology 2004 (3.01 MB) Marika Kärkkäinen et al., Nature Immunology 2004, supplementary data 1 (1.27 MB) Marika Kärkkäinen et al., Nature Immunology 2004, supplementary data 2 (1.23 MB). Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation. J Clin Invest [Internet]. 2005;115(2):247 - 57. http://view.ncbi.nlm.nih.gov/pubmed/15668734 Peter Baluk et al., Journal of Clinical Investigation 2005 (1.89 MB)
Peter Baluk et al., Journal of Clinical Investigation 2005 (1.89 MB). Vascular endothelial cell growth factor receptor 3-mediated activation of lymphatic endothelium is crucial for tumor cell entry and spread via lymphatic vessels. Cancer Res [Internet]. 2005;65(11):4739 - 46. http://view.ncbi.nlm.nih.gov/pubmed/15930292 Yulong He et al., Cancer Research 2005 (1.82 MB)
Yulong He et al., Cancer Research 2005 (1.82 MB). Functional interaction of VEGF-C and VEGF-D with neuropilin receptors. FASEB J [Internet]. 2006;20(9):1462 - 72. http://view.ncbi.nlm.nih.gov/pubmed/16816121 Terhi Kärpänen et al., FASEB Journal 2006 (2.51 MB)
Terhi Kärpänen et al., FASEB Journal 2006 (2.51 MB). Vascular endothelial growth factor (VEGF)/VEGF-C mosaic molecules reveal specificity determinants and feature novel receptor binding patterns. J Biol Chem [Internet]. 2006;281(17):12187 - 95. http://view.ncbi.nlm.nih.gov/pubmed/16505489 Michael Jeltsch et al., The Journal of Biological Chemistry 2006 (1.04 MB) Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 1 (1.01 MB) Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 2 (596.06 KB) Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 3 (738.98 KB) Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 4 (710.03 KB) Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 5 (163.64 KB)
Michael Jeltsch et al., The Journal of Biological Chemistry 2006 (1.04 MB) Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 1 (1.01 MB) Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 2 (596.06 KB) Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 3 (738.98 KB) Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 4 (710.03 KB) Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 5 (163.64 KB)VEGF Receptors. Teoksessa Sigma-RBI Handbook of Receptor Classification and Signal Transduction [Internet]. 5. p. Sigma; 2006. http://www.sigmaaldrich.com/technical-documents/articles/biology/rbi-handbook.html Sigma-RBI Handbook of Receptor Classification and Signal Transduction: VEGF Receptors (263.92 KB)
Sigma-RBI Handbook of Receptor Classification and Signal Transduction: VEGF Receptors (263.92 KB). Distinct architecture of lymphatic vessels induced by chimeric vascular endothelial growth factor-C/vascular endothelial growth factor heparin-binding domain fusion proteins. Circ Res [Internet]. 2007;100(10):1468 - 75. http://view.ncbi.nlm.nih.gov/pubmed/17478733 Tuomas Tammela et al., Circulation Research 2007 (1.1 MB)
Tuomas Tammela et al., Circulation Research 2007 (1.1 MB). Enhanced capillary formation stimulated by a chimeric vascular endothelial growth factor/vascular endothelial growth factor-C silk domain fusion protein. Circ Res [Internet]. 2007;100(10):1460 - 7. http://view.ncbi.nlm.nih.gov/pubmed/17478734 Salla Keskitalo et al., Circulation Research 2007 (1.98 MB)
Salla Keskitalo et al., Circulation Research 2007 (1.98 MB)Inhibiton of VEGF-C-induced VEGFR-3 activity and lymphatic endothelial cell function by the tyrosine kinase inhibitor AZD2171. Teoksessa 98th Annual Meeting of the American-Association-for-Cancer-Research [Internet]. Los Angeles, CA: American Association for Cancer Research; 2007. http://dx.doi.org/10.1158/0008-5472.CAN-07-5809 Heckman et al. - 2007 - Inhibiton of VEGF-C-induced VEGFR-3 activity and l.pdf (236.37 KB)
Heckman et al. - 2007 - Inhibiton of VEGF-C-induced VEGFR-3 activity and l.pdf (236.37 KB). Overexpression of vascular endothelial growth factor-B in mouse heart alters cardiac lipid metabolism and induces myocardial hypertrophy. Circ Res [Internet]. 2008;103(9):1018 - 26. http://view.ncbi.nlm.nih.gov/pubmed/18757827 Terhi Kärpänen et al., Circulation Research 2008 (898.27 KB) Terhi Kärpänen et al., Circulation Research 2008, supplement (1.56 MB)
Terhi Kärpänen et al., Circulation Research 2008 (898.27 KB) Terhi Kärpänen et al., Circulation Research 2008, supplement (1.56 MB). Reevaluation of the role of VEGF-B suggests a restricted role in the revascularization of the ischemic myocardium. Arterioscler Thromb Vasc Biol [Internet]. 2008;28(9):1614 - 20. http://view.ncbi.nlm.nih.gov/pubmed/18511699 Xuri Li et al., Arteriosclerosis, Thrombosis, and Vascular Biology 2008 (738.26 KB) Xuri Li et al., Arteriosclerosis, Thrombosis, and Vascular Biology 2008, data supplement (1012.6 KB)
Xuri Li et al., Arteriosclerosis, Thrombosis, and Vascular Biology 2008 (738.26 KB) Xuri Li et al., Arteriosclerosis, Thrombosis, and Vascular Biology 2008, data supplement (1012.6 KB). The tyrosine kinase inhibitor cediranib blocks ligand-induced vascular endothelial growth factor receptor-3 activity and lymphangiogenesis. Cancer Res [Internet]. 2008;68(12):4754 - 62. http://view.ncbi.nlm.nih.gov/pubmed/18559522 Caroline Heckman et al., Cancer Research 2008 (504.8 KB)
Caroline Heckman et al., Cancer Research 2008 (504.8 KB). Activated forms of VEGF-C and VEGF-D provide improved vascular function in skeletal muscle. Circ Res [Internet]. 2009;104(11):1302 - 12. http://view.ncbi.nlm.nih.gov/pubmed/19443835 Andrey Anisimov et al., Circulation Research 2009 (8.03 MB) Andrey Anisimov et al., Circulation Research 2009, supplement (5.9 MB)
Andrey Anisimov et al., Circulation Research 2009 (8.03 MB) Andrey Anisimov et al., Circulation Research 2009, supplement (5.9 MB). Claudin-like protein 24 interacts with the VEGFR-2 and VEGFR-3 pathways and regulates lymphatic vessel development. Genes Dev [Internet]. 2010;24(9):875 - 80. http://view.ncbi.nlm.nih.gov/pubmed/20439428 Pipsa Saharinen et al., Genes & Development 2010 (1.2 MB) Pipsa Saharinen et al., Genes & Development 2010, supplement (9.15 MB)
Pipsa Saharinen et al., Genes & Development 2010 (1.2 MB) Pipsa Saharinen et al., Genes & Development 2010, supplement (9.15 MB). Effective suppression of vascular network formation by combination of antibodies blocking VEGFR ligand binding and receptor dimerization. Cancer Cell [Internet]. 2010;18(6):630 - 40. http://view.ncbi.nlm.nih.gov/pubmed/21130043 Denis Tvorogov et al., Cancer Cell 2010 (1.3 MB) Denis Tvorogov et al., Cancer Cell 2010, supplement (828.69 KB)
Denis Tvorogov et al., Cancer Cell 2010 (1.3 MB) Denis Tvorogov et al., Cancer Cell 2010, supplement (828.69 KB). Structural determinants of growth factor binding and specificity by VEGF receptor 2. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2010;107(6):2425 - 30. http://view.ncbi.nlm.nih.gov/pubmed/20145116 Veli-Matti Leppänen et al. PNAS 2010 (1 MB) Veli-Matti Leppänen et al. PNAS 2010, supporting information (2.23 MB)
Veli-Matti Leppänen et al. PNAS 2010 (1 MB) Veli-Matti Leppänen et al. PNAS 2010, supporting information (2.23 MB). Suppressive effects of vascular endothelial growth factor-B on tumor growth in a mouse model of pancreatic neuroendocrine tumorigenesis. PLoS ONE [Internet]. 2010;5(11):e14109. http://view.ncbi.nlm.nih.gov/pubmed/21124841 Imke Albrecht et al., PLoS One 2010 (3.37 MB)
Imke Albrecht et al., PLoS One 2010 (3.37 MB). Vascular endothelial growth factor-B acts as a coronary growth factor in transgenic rats without inducing angiogenesis, vascular leak, or inflammation. Circulation [Internet]. 2010;122(17):1725 - 33. http://view.ncbi.nlm.nih.gov/pubmed/20937974 Maija Bry et al., Circulation 2010 (2.23 MB) Maija Bry et al., Circulation 2010, supplement (17.77 MB)
Maija Bry et al., Circulation 2010 (2.23 MB) Maija Bry et al., Circulation 2010, supplement (17.77 MB). Structural determinants of vascular endothelial growth factor-D receptor binding and specificity. Blood [Internet]. 2011;117(5):1507 - 15. http://view.ncbi.nlm.nih.gov/pubmed/21148085 Veli-Matti Leppänen & Michael Jeltsch et al., Blood 2011 (1.17 MB) Veli-Matti Leppänen & Michael Jeltsch et al. Blood 2011, supplementary data (342.97 KB)
Veli-Matti Leppänen & Michael Jeltsch et al., Blood 2011 (1.17 MB) Veli-Matti Leppänen & Michael Jeltsch et al. Blood 2011, supplementary data (342.97 KB)