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VEGF-C Protects the Integrity of Bone Marrow Perivascular Niche
. Blood [Internet]. 2020;:accepted - for publication.
https://ashpublications.org/blood/article/doi/10.1182/blood.2020005699/463465/VEGF-C-Protects-the-Integrity-of-Bone-Marrow
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Fang et al. 2020 - VEGF-C protects the integrity of bone marrow perivascular niche
(6 MB)
VEGF Receptors
. Teoksessa Sigma-RBI Handbook of Receptor Classification and Signal Transduction [Internet]. 5. p. Sigma; 2006.
http://www.sigmaaldrich.com/technical-documents/articles/biology/rbi-handbook.html
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Sigma-RBI Handbook of Receptor Classification and Signal Transduction: VEGF Receptors
(263.92 KB)
Gerhardt H
,
Golding M
,
Fruttiger M
,
Ruhrberg C
,
Lundkvist A
,
Abramsson A
, ym.
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VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia
. J Cell Biol [Internet]. 2003;161(6):1163 - 77.
http://view.ncbi.nlm.nih.gov/pubmed/12810700
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Holger Gerhardt et al., The Journal of Biological Chemistry 2003
(2.24 MB)
Bry M
,
Kivelä R
,
Holopainen T
,
Anisimov A
,
Tammela T
,
Soronen J
, ym.
.
Vascular endothelial growth factor-B acts as a coronary growth factor in transgenic rats without inducing angiogenesis, vascular leak, or inflammation
. Circulation [Internet]. 2010;122(17):1725 - 33.
http://view.ncbi.nlm.nih.gov/pubmed/20937974
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Maija Bry et al., Circulation 2010
(2.23 MB)
Maija Bry et al., Circulation 2010, supplement
(17.77 MB)
Jeltsch M
,
Karpanen T
,
Strandin T
,
Aho K
,
Lankinen H
,
Alitalo K
.
Vascular endothelial growth factor (VEGF)/VEGF-C mosaic molecules reveal specificity determinants and feature novel receptor binding patterns
. J Biol Chem [Internet]. 2006;281(17):12187 - 95.
http://view.ncbi.nlm.nih.gov/pubmed/16505489
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Michael Jeltsch et al., The Journal of Biological Chemistry 2006
(1.04 MB)
Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 1
(1.01 MB)
Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 2
(596.06 KB)
Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 3
(738.98 KB)
Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 4
(710.03 KB)
Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 5
(163.64 KB)
Karkkainen MJ
,
Haiko P
,
Sainio K
,
Partanen J
,
Taipale J
,
Petrova TV
, ym.
.
Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins
. Nat Immunol [Internet]. 2004;5(1):74 - 80.
http://view.ncbi.nlm.nih.gov/pubmed/14634646
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Marika Kärkkäinen et al., Nature Immunology 2004
(3.01 MB)
Marika Kärkkäinen et al., Nature Immunology 2004, supplementary data 1
(1.27 MB)
Marika Kärkkäinen et al., Nature Immunology 2004, supplementary data 2
(1.23 MB)
He Y
,
Rajantie I
,
Pajusola K
,
Jeltsch M
,
Holopainen T
,
Yla-Herttuala S
, ym.
.
Vascular endothelial cell growth factor receptor 3-mediated activation of lymphatic endothelium is crucial for tumor cell entry and spread via lymphatic vessels
. Cancer Res [Internet]. 2005;65(11):4739 - 46.
http://view.ncbi.nlm.nih.gov/pubmed/15930292
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Yulong He et al., Cancer Research 2005
(1.82 MB)
T
Heckman CA
,
Holopainen T
,
Wirzenius M
,
Keskitalo S
,
Jeltsch M
,
Ylä-Herttuala S
, ym.
.
The tyrosine kinase inhibitor cediranib blocks ligand-induced vascular endothelial growth factor receptor-3 activity and lymphangiogenesis
. Cancer Res [Internet]. 2008;68(12):4754 - 62.
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Caroline Heckman et al., Cancer Research 2008
(504.8 KB)
A truncation allele in vascular endothelial growth factor c reveals distinct modes of signaling during lymphatic and vascular development.
Development. 2013;140(7):1497-506.
PubMed
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Villefranc 2013
(7.86 MB)
The TIE Receptor Family
. Teoksessa Receptor Tyrosine Kinases: Family and Subfamilies [Internet]. Springer International Publishing; 2015. ss. 743-775.
https://link.springer.com/content/pdf/10.1007%2F978-3-319-11888-8_16.pdf
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S
Albrecht I
,
Kopfstein L
,
Strittmatter K
,
Schomber T
,
Falkevall A
,
Hagberg CE
, ym.
.
Suppressive effects of vascular endothelial growth factor-B on tumor growth in a mouse model of pancreatic neuroendocrine tumorigenesis
. PLoS ONE [Internet]. 2010;5(11):e14109.
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Imke Albrecht et al., PLoS One 2010
(3.37 MB)
Leppänen V-M
,
Jeltsch M
,
Anisimov A
,
Tvorogov D
,
Aho K
,
Kalkkinen N
, ym.
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Structural determinants of vascular endothelial growth factor-D receptor binding and specificity
. Blood [Internet]. 2011;117(5):1507 - 15.
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Veli-Matti Leppänen & Michael Jeltsch et al., Blood 2011
(1.17 MB)
Veli-Matti Leppänen & Michael Jeltsch et al. Blood 2011, supplementary data
(342.97 KB)
Leppänen V-M
,
Prota AE
,
Jeltsch M
,
Anisimov A
,
Kalkkinen N
,
Strandin T
, ym.
.
Structural determinants of growth factor binding and specificity by VEGF receptor 2
. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2010;107(6):2425 - 30.
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Veli-Matti Leppänen et al. PNAS 2010
(1 MB)
Veli-Matti Leppänen et al. PNAS 2010, supporting information
(2.23 MB)
Structural and mechanistic insights into VEGF receptor 3 ligand binding and activation
. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2013;110(32):12960 - 12965.
http://www.pnas.org/content/110/32/12960.long
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R
Li X
,
Tjwa M
,
Van Hove I
,
Enholm B
,
Neven E
,
Paavonen K
, ym.
.
Reevaluation of the role of VEGF-B suggests a restricted role in the revascularization of the ischemic myocardium
. Arterioscler Thromb Vasc Biol [Internet]. 2008;28(9):1614 - 20.
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Xuri Li et al., Arteriosclerosis, Thrombosis, and Vascular Biology 2008
(738.26 KB)
Xuri Li et al., Arteriosclerosis, Thrombosis, and Vascular Biology 2008, data supplement
(1012.6 KB)
Receptor Tyrosine Kinase-Mediated Angiogenesis
. Cold Spring Harbor Perspectives in Biology [Internet]. 2013;5(9).
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Jeltsch et al. (2013): Tyrosine Kinase-Mediated Angiogenesis. CSH Persp Biol
(934.46 KB)
P
Baluk P
,
Tammela T
,
Ator E
,
Lyubynska N
,
Achen MG
,
Hicklin DJ
, ym.
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Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation
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Peter Baluk et al., Journal of Clinical Investigation 2005
(1.89 MB)
O
Karpanen T
,
Bry M
,
Ollila HM
,
Seppänen-Laakso T
,
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,
Leskinen H
, ym.
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Overexpression of vascular endothelial growth factor-B in mouse heart alters cardiac lipid metabolism and induces myocardial hypertrophy
. Circ Res [Internet]. 2008;103(9):1018 - 26.
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Terhi Kärpänen et al., Circulation Research 2008
(898.27 KB)
Terhi Kärpänen et al., Circulation Research 2008, supplement
(1.56 MB)
L
Jeltsch M
,
Alitalo K
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Lymphatic-to-blood vessel transdifferentiation in zebrafish
. Nature Cardiovascular Research [Internet]. 2022;1(6):539 - 541.
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K
Jha SK
,
Rauniyar K
,
Chronowska E
,
Mattonet K
,
Maina EW
,
Koistinen H
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KLK3/PSA and cathepsin D activate VEGF-C and VEGF-D
. eLife [Internet]. 2019;8:e44478.
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Jha & Rauniyar et al. 2019
(3.84 MB)
I
Veikkola T
,
Lohela M
,
Ikenberg K
,
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,
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, ym.
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Intrinsic versus microenvironmental regulation of lymphatic endothelial cell phenotype and function
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Tanja Veikkola et al., FASEB Journal 2006
(598.77 KB)
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Jeltsch M
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,
Alitalo K
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Michael Jeltsch et al., Cell and Tissue Research 2003
(562.33 KB)
F
Kärpänen T
,
Heckman CA
,
Keskitalo S
,
Jeltsch M
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,
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, ym.
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Functional interaction of VEGF-C and VEGF-D with neuropilin receptors
. FASEB J [Internet]. 2006;20(9):1462 - 72.
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Terhi Kärpänen et al., FASEB Journal 2006
(2.51 MB)
Functional Importance of a Proteoglycan Co-Receptor in Pathologic Lymphangiogenesis
. Circulation Research [Internet]. 2016;119(2):210-221.
http://circres.ahajournals.org/content/early/2016/05/25/CIRCRESAHA.116.308504
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Johns et al. 2016: Functional Importance of a Proteoglycan Co-Receptor in Pathologic Lymphangiogenesis
(3.69 MB)
Johns et al. 2016: Functional Importance of a Proteoglycan Co-Receptor in Pathologic Lymphangiogenesis: Supplemental Data
(3.3 MB)
Functional Dissection of the CCBE1 Protein: A Crucial Requirement for the Collagen Repeat Domain.
Circ Res [Internet]. 2015;116(10):1660-1669.
http://circres.ahajournals.org/content/116/10/1660.long
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