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2013
Anisimov A
,
Tvorogov D
,
Alitalo A
,
Leppänen V-M
,
An Y
,
Han EC
, et al.
.
Vascular endothelial growth factor-angiopoietin chimera with improved properties for therapeutic angiogenesis
. Circulation. 2013;127(4):424-434.
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Anisimov 2013
(6.56 MB)
Anisimov 2013 Supplement
(4.93 MB)
Anisimov A
,
Tvorogov D
,
Alitalo A
,
Leppänen V-M
,
An Y
,
Han EC
, et al.
.
Vascular endothelial growth factor-angiopoietin chimera with improved properties for therapeutic angiogenesis
. Circulation. 2013;127(4):424-434.
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BibTeX
RTF
Tagged
MARC
EndNote XML
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Anisimov 2013
(6.56 MB)
Anisimov 2013 Supplement
(4.93 MB)
Anisimov A
,
Tvorogov D
,
Alitalo A
,
Leppänen V-M
,
An Y
,
Han EC
, et al.
.
Vascular endothelial growth factor-angiopoietin chimera with improved properties for therapeutic angiogenesis
. Circulation. 2013;127(4):424-434.
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BibTeX
RTF
Tagged
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RIS
Anisimov 2013
(6.56 MB)
Anisimov 2013 Supplement
(4.93 MB)
2012
Krebs R
,
Tikkanen JM
,
Ropponen JO
,
Jeltsch M
,
Jokinen JJ
,
Ylä-Herttuala S
, et al.
.
Critical role of VEGF-C/VEGFR-3 signaling in innate and adaptive immune responses in experimental obliterative bronchiolitis.
Am J Pathol. 2012;181(5):1607-20.
PubMed
DOI
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2011
Leppänen V-M
,
Jeltsch M
,
Anisimov A
,
Tvorogov D
,
Aho K
,
Kalkkinen N
, et al.
.
Structural determinants of vascular endothelial growth factor-D receptor binding and specificity
. Blood [Internet]. 2011;117(5):1507 - 15.
http://view.ncbi.nlm.nih.gov/pubmed/21148085
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Veli-Matti Leppänen & Michael Jeltsch et al., Blood 2011
(1.17 MB)
Veli-Matti Leppänen & Michael Jeltsch et al. Blood 2011, supplementary data
(342.97 KB)
Krebs R
,
Tikkanen JM
,
Ropponen JO
,
Jeltsch M
,
Jokinen JJ
,
Ylä-Herttuala S
, et al.
.
VEGF-C/VEGFR-3 Signaling Regulates Inflammatory Response in Development of Obliterative Airway Disease
. Journal of Heart and Lung Transplantation. 2011;30:S118 - S118.
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Krebs R
,
Tikkanen JM
,
Ropponen JO
,
Jeltsch M
,
Jokinen JJ
,
Ylä-Herttuala S
, et al.
.
VEGF-C/VEGFR-3 Signaling Regulates Inflammatory Response in Development of Obliterative Airway Disease
. Journal of Heart and Lung Transplantation. 2011;30:S118 - S118.
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2010
Tvorogov D
,
Anisimov A
,
Zheng W
,
Leppänen V-M
,
Tammela T
,
Laurinavicius S
, et al.
.
Effective suppression of vascular network formation by combination of antibodies blocking VEGFR ligand binding and receptor dimerization
. Cancer Cell [Internet]. 2010;18(6):630 - 40.
http://view.ncbi.nlm.nih.gov/pubmed/21130043
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Denis Tvorogov et al., Cancer Cell 2010
(1.3 MB)
Denis Tvorogov et al., Cancer Cell 2010, supplement
(828.69 KB)
Leppänen V-M
,
Prota AE
,
Jeltsch M
,
Anisimov A
,
Kalkkinen N
,
Strandin T
, et al.
.
Structural determinants of growth factor binding and specificity by VEGF receptor 2
. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2010;107(6):2425 - 30.
http://view.ncbi.nlm.nih.gov/pubmed/20145116
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Veli-Matti Leppänen et al. PNAS 2010
(1 MB)
Veli-Matti Leppänen et al. PNAS 2010, supporting information
(2.23 MB)
Albrecht I
,
Kopfstein L
,
Strittmatter K
,
Schomber T
,
Falkevall A
,
Hagberg CE
, et al.
.
Suppressive effects of vascular endothelial growth factor-B on tumor growth in a mouse model of pancreatic neuroendocrine tumorigenesis
. PLoS ONE [Internet]. 2010;5(11):e14109.
http://view.ncbi.nlm.nih.gov/pubmed/21124841
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Imke Albrecht et al., PLoS One 2010
(3.37 MB)
Bry M
,
Kivelä R
,
Holopainen T
,
Anisimov A
,
Tammela T
,
Soronen J
, et al.
.
Vascular endothelial growth factor-B acts as a coronary growth factor in transgenic rats without inducing angiogenesis, vascular leak, or inflammation
. Circulation [Internet]. 2010;122(17):1725 - 33.
http://view.ncbi.nlm.nih.gov/pubmed/20937974
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Maija Bry et al., Circulation 2010
(2.23 MB)
Maija Bry et al., Circulation 2010, supplement
(17.77 MB)
Bry M
,
Kivelä R
,
Holopainen T
,
Anisimov A
,
Tammela T
,
Soronen J
, et al.
.
Vascular endothelial growth factor-B acts as a coronary growth factor in transgenic rats without inducing angiogenesis, vascular leak, or inflammation
. Circulation [Internet]. 2010;122(17):1725 - 33.
http://view.ncbi.nlm.nih.gov/pubmed/20937974
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Maija Bry et al., Circulation 2010
(2.23 MB)
Maija Bry et al., Circulation 2010, supplement
(17.77 MB)
Bry M
,
Kivelä R
,
Holopainen T
,
Anisimov A
,
Tammela T
,
Soronen J
, et al.
.
Vascular endothelial growth factor-B acts as a coronary growth factor in transgenic rats without inducing angiogenesis, vascular leak, or inflammation
. Circulation [Internet]. 2010;122(17):1725 - 33.
http://view.ncbi.nlm.nih.gov/pubmed/20937974
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Maija Bry et al., Circulation 2010
(2.23 MB)
Maija Bry et al., Circulation 2010, supplement
(17.77 MB)
2009
Anisimov A
,
Alitalo A
,
Korpisalo P
,
Soronen J
,
Kaijalainen S
,
Leppänen V-M
, et al.
.
Activated forms of VEGF-C and VEGF-D provide improved vascular function in skeletal muscle
. Circ Res [Internet]. 2009;104(11):1302 - 12.
http://view.ncbi.nlm.nih.gov/pubmed/19443835
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Andrey Anisimov et al., Circulation Research 2009
(8.03 MB)
Andrey Anisimov et al., Circulation Research 2009, supplement
(5.9 MB)
Anisimov A
,
Alitalo A
,
Korpisalo P
,
Soronen J
,
Kaijalainen S
,
Leppänen V-M
, et al.
.
Activated forms of VEGF-C and VEGF-D provide improved vascular function in skeletal muscle
. Circ Res [Internet]. 2009;104(11):1302 - 12.
http://view.ncbi.nlm.nih.gov/pubmed/19443835
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Andrey Anisimov et al., Circulation Research 2009
(8.03 MB)
Andrey Anisimov et al., Circulation Research 2009, supplement
(5.9 MB)
2008
Karpanen T
,
Bry M
,
Ollila HM
,
Seppänen-Laakso T
,
Liimatta E
,
Leskinen H
, et al.
.
Overexpression of vascular endothelial growth factor-B in mouse heart alters cardiac lipid metabolism and induces myocardial hypertrophy
. Circ Res [Internet]. 2008;103(9):1018 - 26.
http://view.ncbi.nlm.nih.gov/pubmed/18757827
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Terhi Kärpänen et al., Circulation Research 2008
(898.27 KB)
Terhi Kärpänen et al., Circulation Research 2008, supplement
(1.56 MB)
Karpanen T
,
Bry M
,
Ollila HM
,
Seppänen-Laakso T
,
Liimatta E
,
Leskinen H
, et al.
.
Overexpression of vascular endothelial growth factor-B in mouse heart alters cardiac lipid metabolism and induces myocardial hypertrophy
. Circ Res [Internet]. 2008;103(9):1018 - 26.
http://view.ncbi.nlm.nih.gov/pubmed/18757827
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Terhi Kärpänen et al., Circulation Research 2008
(898.27 KB)
Terhi Kärpänen et al., Circulation Research 2008, supplement
(1.56 MB)
Heckman CA
,
Holopainen T
,
Wirzenius M
,
Keskitalo S
,
Jeltsch M
,
Ylä-Herttuala S
, et al.
.
The tyrosine kinase inhibitor cediranib blocks ligand-induced vascular endothelial growth factor receptor-3 activity and lymphangiogenesis
. Cancer Res [Internet]. 2008;68(12):4754 - 62.
http://view.ncbi.nlm.nih.gov/pubmed/18559522
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Caroline Heckman et al., Cancer Research 2008
(504.8 KB)
2007
Keskitalo S
,
Tammela T
,
Lyytikka J
,
Karpanen T
,
Jeltsch M
,
Markkanen J
, et al.
.
Enhanced capillary formation stimulated by a chimeric vascular endothelial growth factor/vascular endothelial growth factor-C silk domain fusion protein
. Circ Res [Internet]. 2007;100(10):1460 - 7.
http://view.ncbi.nlm.nih.gov/pubmed/17478734
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Salla Keskitalo et al., Circulation Research 2007
(1.98 MB)
Keskitalo S
,
Tammela T
,
Lyytikka J
,
Karpanen T
,
Jeltsch M
,
Markkanen J
, et al.
.
Enhanced capillary formation stimulated by a chimeric vascular endothelial growth factor/vascular endothelial growth factor-C silk domain fusion protein
. Circ Res [Internet]. 2007;100(10):1460 - 7.
http://view.ncbi.nlm.nih.gov/pubmed/17478734
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Salla Keskitalo et al., Circulation Research 2007
(1.98 MB)
Heckman CA
,
Holopainen T
,
Wirzenius M
,
Keskitalo S
,
Jeltsch M
,
Wedge SR
, et al.
.
Inhibiton of VEGF-C-induced VEGFR-3 activity and lymphatic endothelial cell function by the tyrosine kinase inhibitor AZD2171
. In 98th Annual Meeting of the American-Association-for-Cancer-Research [Internet]. Los Angeles, CA: American Association for Cancer Research; 2007.
http://dx.doi.org/10.1158/0008-5472.CAN-07-5809
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Heckman et al. - 2007 - Inhibiton of VEGF-C-induced VEGFR-3 activity and l.pdf
(236.37 KB)
2006
Kärpänen T
,
Heckman CA
,
Keskitalo S
,
Jeltsch M
,
Ollila H
,
Neufeld G
, et al.
.
Functional interaction of VEGF-C and VEGF-D with neuropilin receptors
. FASEB J [Internet]. 2006;20(9):1462 - 72.
http://view.ncbi.nlm.nih.gov/pubmed/16816121
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Terhi Kärpänen et al., FASEB Journal 2006
(2.51 MB)
Kärpänen T
,
Heckman CA
,
Keskitalo S
,
Jeltsch M
,
Ollila H
,
Neufeld G
, et al.
.
Functional interaction of VEGF-C and VEGF-D with neuropilin receptors
. FASEB J [Internet]. 2006;20(9):1462 - 72.
http://view.ncbi.nlm.nih.gov/pubmed/16816121
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Terhi Kärpänen et al., FASEB Journal 2006
(2.51 MB)
Jeltsch M
,
Karpanen T
,
Strandin T
,
Aho K
,
Lankinen H
,
Alitalo K
.
Vascular endothelial growth factor (VEGF)/VEGF-C mosaic molecules reveal specificity determinants and feature novel receptor binding patterns
. J Biol Chem [Internet]. 2006;281(17):12187 - 95.
http://view.ncbi.nlm.nih.gov/pubmed/16505489
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Michael Jeltsch et al., The Journal of Biological Chemistry 2006
(1.04 MB)
Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 1
(1.01 MB)
Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 2
(596.06 KB)
Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 3
(738.98 KB)
Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 4
(710.03 KB)
Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 5
(163.64 KB)
2004
Karkkainen MJ
,
Haiko P
,
Sainio K
,
Partanen J
,
Taipale J
,
Petrova TV
, et al.
.
Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins
. Nat Immunol [Internet]. 2004;5(1):74 - 80.
http://view.ncbi.nlm.nih.gov/pubmed/14634646
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Marika Kärkkäinen et al., Nature Immunology 2004
(3.01 MB)
Marika Kärkkäinen et al., Nature Immunology 2004, supplementary data 1
(1.27 MB)
Marika Kärkkäinen et al., Nature Immunology 2004, supplementary data 2
(1.23 MB)
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