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. Signalling via VEGFR-3 is sufficient for lymphangiogenesis in transgenic mice. In Molecular Targets and Cancer Therapeutics: Discovery, Biology, and Clinical Applications. Miami Beach, Florida; 2001. 
Jussila et al., 2001 (279.47 KB)
Jussila et al., 2001 (279.47 KB). Activated forms of VEGF-C and VEGF-D provide improved vascular function in skeletal muscle. Circ Res [Internet]. 2009;104(11):1302 - 12. http://view.ncbi.nlm.nih.gov/pubmed/19443835 Andrey Anisimov et al., Circulation Research 2009 (8.03 MB) Andrey Anisimov et al., Circulation Research 2009, supplement (5.9 MB)
Andrey Anisimov et al., Circulation Research 2009 (8.03 MB) Andrey Anisimov et al., Circulation Research 2009, supplement (5.9 MB). Adenoviral expression of vascular endothelial growth factor-C induces lymphangiogenesis in the skin. Circ Res [Internet]. 2001;88(6):623 - 9. http://view.ncbi.nlm.nih.gov/pubmed/11282897 Bernd Enholm et al., Circulation Research 2001 (2.93 MB)
Bernd Enholm et al., Circulation Research 2001 (2.93 MB). Adenoviral VEGF-C overexpression induces blood vessel enlargement, tortuosity, and leakiness but no sprouting angiogenesis in the skin or mucous membranes. FASEB J [Internet]. 2002;16(9):1041 - 9. http://view.ncbi.nlm.nih.gov/pubmed/12087065 Anne Saaristo et al., FASEB Journal 2002 (966.08 KB)
Anne Saaristo et al., FASEB Journal 2002 (966.08 KB). Claudin-like protein 24 interacts with the VEGFR-2 and VEGFR-3 pathways and regulates lymphatic vessel development. Genes Dev [Internet]. 2010;24(9):875 - 80. http://view.ncbi.nlm.nih.gov/pubmed/20439428 Pipsa Saharinen et al., Genes & Development 2010 (1.2 MB) Pipsa Saharinen et al., Genes & Development 2010, supplement (9.15 MB)
Pipsa Saharinen et al., Genes & Development 2010 (1.2 MB) Pipsa Saharinen et al., Genes & Development 2010, supplement (9.15 MB). Hyperplasia of lymphatic vessels in VEGF-C transgenic mice. Science (80- ) [Internet]. 1997;276(5317):1423 - 5. http://view.ncbi.nlm.nih.gov/pubmed/9162011 Michael Jeltsch et al., Science 1997 (293.65 KB)
Michael Jeltsch et al., Science 1997 (293.65 KB). Intrinsic versus microenvironmental regulation of lymphatic endothelial cell phenotype and function. FASEB J [Internet]. 2003;17(14):2006 - 13. http://view.ncbi.nlm.nih.gov/pubmed/14597670 Tanja Veikkola et al., FASEB Journal 2006 (598.77 KB)
Tanja Veikkola et al., FASEB Journal 2006 (598.77 KB). KLK3/PSA and cathepsin D activate VEGF-C and VEGF-D. eLife [Internet]. 2019;8:e44478. https://elifesciences.org/articles/44478 Jha & Rauniyar et al. 2019 (3.84 MB)
Jha & Rauniyar et al. 2019 (3.84 MB). Lymphatics and the eye. [Finnish]. Duodecim Lääketieteellinen Aikakauskirja [Internet]. 2020;136(16):1777-1788. https://www.duodecimlehti.fi/lehti/2020/16/duo15739 Gucciardo et al. Lymphatics and the Eye (English version). (3.31 MB)
Gucciardo et al. Lymphatics and the Eye (English version). (3.31 MB). Overexpression of vascular endothelial growth factor-B in mouse heart alters cardiac lipid metabolism and induces myocardial hypertrophy. Circ Res [Internet]. 2008;103(9):1018 - 26. http://view.ncbi.nlm.nih.gov/pubmed/18757827 Terhi Kärpänen et al., Circulation Research 2008 (898.27 KB) Terhi Kärpänen et al., Circulation Research 2008, supplement (1.56 MB)
Terhi Kärpänen et al., Circulation Research 2008 (898.27 KB) Terhi Kärpänen et al., Circulation Research 2008, supplement (1.56 MB). Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation. J Clin Invest [Internet]. 2005;115(2):247 - 57. http://view.ncbi.nlm.nih.gov/pubmed/15668734 Peter Baluk et al., Journal of Clinical Investigation 2005 (1.89 MB)
Peter Baluk et al., Journal of Clinical Investigation 2005 (1.89 MB). The Proteolytic Activation of Vascular Endothelial Growth Factor-C. Lymphologie in Forschung und Praxis [Internet]. 2019;23(2):88 - 98. https://doi.org/10.5281/zenodo.3629263 English version: Lackner et al. 2019 (2.94 MB) German version: Lackner et al. 2019 (673.37 KB)
English version: Lackner et al. 2019 (2.94 MB) German version: Lackner et al. 2019 (673.37 KB). Proteolytic processing regulates receptor specificity and activity of VEGF-C. EMBO J [Internet]. 1997;16(13):3898 - 911. http://view.ncbi.nlm.nih.gov/pubmed/9233800 Vladimir Joukov et al., EMBO Journal 1997 (729.21 KB)
Vladimir Joukov et al., EMBO Journal 1997 (729.21 KB). Proteolytic processing regulates receptor specificity and activity of VEGF-C. EMBO J [Internet]. 1997;16(13):3898 - 911. http://view.ncbi.nlm.nih.gov/pubmed/9233800 Vladimir Joukov et al., EMBO Journal 1997 (729.21 KB)
Vladimir Joukov et al., EMBO Journal 1997 (729.21 KB). Reevaluation of the role of VEGF-B suggests a restricted role in the revascularization of the ischemic myocardium. Arterioscler Thromb Vasc Biol [Internet]. 2008;28(9):1614 - 20. http://view.ncbi.nlm.nih.gov/pubmed/18511699 Xuri Li et al., Arteriosclerosis, Thrombosis, and Vascular Biology 2008 (738.26 KB) Xuri Li et al., Arteriosclerosis, Thrombosis, and Vascular Biology 2008, data supplement (1012.6 KB)
Xuri Li et al., Arteriosclerosis, Thrombosis, and Vascular Biology 2008 (738.26 KB) Xuri Li et al., Arteriosclerosis, Thrombosis, and Vascular Biology 2008, data supplement (1012.6 KB). Reevaluation of the role of VEGF-B suggests a restricted role in the revascularization of the ischemic myocardium. Arterioscler Thromb Vasc Biol [Internet]. 2008;28(9):1614 - 20. http://view.ncbi.nlm.nih.gov/pubmed/18511699 Xuri Li et al., Arteriosclerosis, Thrombosis, and Vascular Biology 2008 (738.26 KB) Xuri Li et al., Arteriosclerosis, Thrombosis, and Vascular Biology 2008, data supplement (1012.6 KB)
Xuri Li et al., Arteriosclerosis, Thrombosis, and Vascular Biology 2008 (738.26 KB) Xuri Li et al., Arteriosclerosis, Thrombosis, and Vascular Biology 2008, data supplement (1012.6 KB). Signalling via vascular endothelial growth factor receptor-3 is sufficient for lymphangiogenesis in transgenic mice. EMBO J [Internet]. 2001;20(6):1223 - 31. http://view.ncbi.nlm.nih.gov/pubmed/11250889 Tanja Veikkola et al., EMBO Journal 2001 (491.14 KB)
Tanja Veikkola et al., EMBO Journal 2001 (491.14 KB). Structural determinants of growth factor binding and specificity by VEGF receptor 2. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2010;107(6):2425 - 30. http://view.ncbi.nlm.nih.gov/pubmed/20145116 Veli-Matti Leppänen et al. PNAS 2010 (1 MB) Veli-Matti Leppänen et al. PNAS 2010, supporting information (2.23 MB)
Veli-Matti Leppänen et al. PNAS 2010 (1 MB) Veli-Matti Leppänen et al. PNAS 2010, supporting information (2.23 MB). Study of the Synergistic Immunomodulatory and Antifibrotic Effects of Dual-Loaded Budesonide and Serpine1 siRNA Lipid–Polymer Nanoparticles Targeting Macrophage Dysregulation in Tendinopathy. ACS Applied Materials & Interfaces [Internet]. 2024;16(15):18643 - 18657. https://pubs.acs.org/doi/10.1021/acsami.4c02363 López-Cerdá et al. - 2024 - Study of the Synergistic Immunomodulatory and Antifibrotic Effects of Dual-Loaded Budesonide [...] (7.06 MB)
López-Cerdá et al. - 2024 - Study of the Synergistic Immunomodulatory and Antifibrotic Effects of Dual-Loaded Budesonide [...] (7.06 MB). Study of the Synergistic Immunomodulatory and Antifibrotic Effects of Dual-Loaded Budesonide and Serpine1 siRNA Lipid–Polymer Nanoparticles Targeting Macrophage Dysregulation in Tendinopathy. ACS Applied Materials & Interfaces [Internet]. 2024;16(15):18643 - 18657. https://pubs.acs.org/doi/10.1021/acsami.4c02363 López-Cerdá et al. - 2024 - Study of the Synergistic Immunomodulatory and Antifibrotic Effects of Dual-Loaded Budesonide [...] (7.06 MB)
López-Cerdá et al. - 2024 - Study of the Synergistic Immunomodulatory and Antifibrotic Effects of Dual-Loaded Budesonide [...] (7.06 MB). Study of the Synergistic Immunomodulatory and Antifibrotic Effects of Dual-Loaded Budesonide and Serpine1 siRNA Lipid–Polymer Nanoparticles Targeting Macrophage Dysregulation in Tendinopathy. ACS Applied Materials & Interfaces [Internet]. 2024;16(15):18643 - 18657. https://pubs.acs.org/doi/10.1021/acsami.4c02363 López-Cerdá et al. - 2024 - Study of the Synergistic Immunomodulatory and Antifibrotic Effects of Dual-Loaded Budesonide [...] (7.06 MB)
López-Cerdá et al. - 2024 - Study of the Synergistic Immunomodulatory and Antifibrotic Effects of Dual-Loaded Budesonide [...] (7.06 MB). Suppressive effects of vascular endothelial growth factor-B on tumor growth in a mouse model of pancreatic neuroendocrine tumorigenesis. PLoS ONE [Internet]. 2010;5(11):e14109. http://view.ncbi.nlm.nih.gov/pubmed/21124841 Imke Albrecht et al., PLoS One 2010 (3.37 MB)
Imke Albrecht et al., PLoS One 2010 (3.37 MB). Suppressive effects of vascular endothelial growth factor-B on tumor growth in a mouse model of pancreatic neuroendocrine tumorigenesis. PLoS ONE [Internet]. 2010;5(11):e14109. http://view.ncbi.nlm.nih.gov/pubmed/21124841 Imke Albrecht et al., PLoS One 2010 (3.37 MB)
Imke Albrecht et al., PLoS One 2010 (3.37 MB). Vascular endothelial growth factor B (VEGF-B) binds to VEGF receptor-1 and regulates plasminogen activator activity in endothelial cells. Proc Natl Acad Sci U S A [Internet]. 1998;95(20):11709 - 14. http://view.ncbi.nlm.nih.gov/pubmed/9751730 Birgitta Olofsson et al., PNAS 1998 (470.59 KB)
Birgitta Olofsson et al., PNAS 1998 (470.59 KB). Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins. Nat Immunol [Internet]. 2004;5(1):74 - 80. http://view.ncbi.nlm.nih.gov/pubmed/14634646 Marika Kärkkäinen et al., Nature Immunology 2004 (3.01 MB) Marika Kärkkäinen et al., Nature Immunology 2004, supplementary data 1 (1.27 MB) Marika Kärkkäinen et al., Nature Immunology 2004, supplementary data 2 (1.23 MB)
Marika Kärkkäinen et al., Nature Immunology 2004 (3.01 MB) Marika Kärkkäinen et al., Nature Immunology 2004, supplementary data 1 (1.27 MB) Marika Kärkkäinen et al., Nature Immunology 2004, supplementary data 2 (1.23 MB)