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Michael Jeltsch et al., Science 1997 (293.65 KB). Proteolytic processing regulates receptor specificity and activity of VEGF-C. EMBO J [Internet]. 1997;16(13):3898 - 911. http://view.ncbi.nlm.nih.gov/pubmed/9233800 Vladimir Joukov et al., EMBO Journal 1997 (729.21 KB)
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Su-Ja Oh et al., Developmental Biology 1997 (3.28 MB). Vascular endothelial growth factor B (VEGF-B) binds to VEGF receptor-1 and regulates plasminogen activator activity in endothelial cells. Proc Natl Acad Sci U S A [Internet]. 1998;95(20):11709 - 14. http://view.ncbi.nlm.nih.gov/pubmed/9751730 Birgitta Olofsson et al., PNAS 1998 (470.59 KB)
Birgitta Olofsson et al., PNAS 1998 (470.59 KB). Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4). Proc Natl Acad Sci U S A [Internet]. 1998;95(2):548 - 53. http://view.ncbi.nlm.nih.gov/pubmed/9435229 Marc Achen et al., PNAS 1998 (447.59 KB)
Marc Achen et al., PNAS 1998 (447.59 KB). Vascular endothelial growth factor (VEGF)-C synergizes with basic fibroblast growth factor and VEGF in the induction of angiogenesis in vitro and alters endothelial cell extracellular proteolytic activity. J Cell Physiol [Internet]. 1998;177(3):439 - 52. http://view.ncbi.nlm.nih.gov/pubmed/9808152 Michael Pepper et al., Journal of Cellular Physiology 1998 (689.97 KB)
Michael Pepper et al., Journal of Cellular Physiology 1998 (689.97 KB). Current biology of VEGF-B and VEGF-C. Curr Opin Biotechnol [Internet]. 1999;10(6):528 - 35. http://view.ncbi.nlm.nih.gov/pubmed/10600689 Birgitta Olofsson et al., Current Opinion in Biotechnology 1999 (577.33 KB)
Birgitta Olofsson et al., Current Opinion in Biotechnology 1999 (577.33 KB). Intravascular adenovirus-mediated VEGF-C gene transfer reduces neointima formation in balloon-denuded rabbit aorta. Circulation [Internet]. 2000;102(18):2262 - 8. http://view.ncbi.nlm.nih.gov/pubmed/11056103 Mikko Hiltunen et al., Circulation 2000 (1.44 MB)
Mikko Hiltunen et al., Circulation 2000 (1.44 MB). Adenoviral expression of vascular endothelial growth factor-C induces lymphangiogenesis in the skin. Circ Res [Internet]. 2001;88(6):623 - 9. http://view.ncbi.nlm.nih.gov/pubmed/11282897 Bernd Enholm et al., Circulation Research 2001 (2.93 MB)
Bernd Enholm et al., Circulation Research 2001 (2.93 MB). Signalling via vascular endothelial growth factor receptor-3 is sufficient for lymphangiogenesis in transgenic mice. EMBO J [Internet]. 2001;20(6):1223 - 31. http://view.ncbi.nlm.nih.gov/pubmed/11250889 Tanja Veikkola et al., EMBO Journal 2001 (491.14 KB)
Tanja Veikkola et al., EMBO Journal 2001 (491.14 KB). Signalling via VEGFR-3 is sufficient for lymphangiogenesis in transgenic mice. In Molecular Targets and Cancer Therapeutics: Discovery, Biology, and Clinical Applications. Miami Beach, Florida; 2001. Jussila et al., 2001 (279.47 KB)
Jussila et al., 2001 (279.47 KB). Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis. EMBO J [Internet]. 2001;20(4):672 - 82. http://view.ncbi.nlm.nih.gov/pubmed/11179212 Stefano Mandriota et al., EMBO Journal 2001 (736.96 KB)
Stefano Mandriota et al., EMBO Journal 2001 (736.96 KB). Adenoviral VEGF-C overexpression induces blood vessel enlargement, tortuosity, and leakiness but no sprouting angiogenesis in the skin or mucous membranes. FASEB J [Internet]. 2002;16(9):1041 - 9. http://view.ncbi.nlm.nih.gov/pubmed/12087065 Anne Saaristo et al., FASEB Journal 2002 (966.08 KB)
Anne Saaristo et al., FASEB Journal 2002 (966.08 KB). VEGFR-3 Ligands and Lymphangiogenesis [Internet]. University of Helsinki. 2002. http://ethesis.helsinki.fi/julkaisut/mat/bioti/vk/jeltsch Michael Jeltsch, PhD Thesis, 2002 (1.75 MB)
Michael Jeltsch, PhD Thesis, 2002 (1.75 MB). Genesis and pathogenesis of lymphatic vessels. Cell Tissue Res [Internet]. 2003;314(1):69 - 84. http://view.ncbi.nlm.nih.gov/pubmed/12942362 Michael Jeltsch et al., Cell and Tissue Research 2003 (562.33 KB)
Michael Jeltsch et al., Cell and Tissue Research 2003 (562.33 KB). Intrinsic versus microenvironmental regulation of lymphatic endothelial cell phenotype and function. FASEB J [Internet]. 2003;17(14):2006 - 13. http://view.ncbi.nlm.nih.gov/pubmed/14597670 Tanja Veikkola et al., FASEB Journal 2006 (598.77 KB)
Tanja Veikkola et al., FASEB Journal 2006 (598.77 KB). VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia. J Cell Biol [Internet]. 2003;161(6):1163 - 77. http://view.ncbi.nlm.nih.gov/pubmed/12810700 Holger Gerhardt et al., The Journal of Biological Chemistry 2003 (2.24 MB)
Holger Gerhardt et al., The Journal of Biological Chemistry 2003 (2.24 MB). Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins. Nat Immunol [Internet]. 2004;5(1):74 - 80. http://view.ncbi.nlm.nih.gov/pubmed/14634646 Marika Kärkkäinen et al., Nature Immunology 2004 (3.01 MB) Marika Kärkkäinen et al., Nature Immunology 2004, supplementary data 1 (1.27 MB) Marika Kärkkäinen et al., Nature Immunology 2004, supplementary data 2 (1.23 MB)
Marika Kärkkäinen et al., Nature Immunology 2004 (3.01 MB) Marika Kärkkäinen et al., Nature Immunology 2004, supplementary data 1 (1.27 MB) Marika Kärkkäinen et al., Nature Immunology 2004, supplementary data 2 (1.23 MB). Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation. J Clin Invest [Internet]. 2005;115(2):247 - 57. http://view.ncbi.nlm.nih.gov/pubmed/15668734 Peter Baluk et al., Journal of Clinical Investigation 2005 (1.89 MB)
Peter Baluk et al., Journal of Clinical Investigation 2005 (1.89 MB). Vascular endothelial cell growth factor receptor 3-mediated activation of lymphatic endothelium is crucial for tumor cell entry and spread via lymphatic vessels. Cancer Res [Internet]. 2005;65(11):4739 - 46. http://view.ncbi.nlm.nih.gov/pubmed/15930292 Yulong He et al., Cancer Research 2005 (1.82 MB)
Yulong He et al., Cancer Research 2005 (1.82 MB). Functional interaction of VEGF-C and VEGF-D with neuropilin receptors. FASEB J [Internet]. 2006;20(9):1462 - 72. http://view.ncbi.nlm.nih.gov/pubmed/16816121 Terhi Kärpänen et al., FASEB Journal 2006 (2.51 MB)
Terhi Kärpänen et al., FASEB Journal 2006 (2.51 MB). Vascular endothelial growth factor (VEGF)/VEGF-C mosaic molecules reveal specificity determinants and feature novel receptor binding patterns. J Biol Chem [Internet]. 2006;281(17):12187 - 95. http://view.ncbi.nlm.nih.gov/pubmed/16505489 Michael Jeltsch et al., The Journal of Biological Chemistry 2006 (1.04 MB) Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 1 (1.01 MB) Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 2 (596.06 KB) Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 3 (738.98 KB) Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 4 (710.03 KB) Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 5 (163.64 KB)
Michael Jeltsch et al., The Journal of Biological Chemistry 2006 (1.04 MB) Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 1 (1.01 MB) Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 2 (596.06 KB) Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 3 (738.98 KB) Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 4 (710.03 KB) Michael Jeltsch et al., The Journal of Biological Chemistry 2006, supplemental data 5 (163.64 KB)