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Veikkola T
,
Lohela M
,
Ikenberg K
,
Mäkinen T
,
Korff T
,
Saaristo A
, et al.
.
Intrinsic versus microenvironmental regulation of lymphatic endothelial cell phenotype and function
. FASEB J [Internet]. 2003;17(14):2006 - 13.
http://view.ncbi.nlm.nih.gov/pubmed/14597670
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Tanja Veikkola et al., FASEB Journal 2006
(598.77 KB)
Veikkola T
,
Jussila L
,
Makinen T
,
Karpanen T
,
Jeltsch M
,
Petrova TV
, et al.
.
Signalling via vascular endothelial growth factor receptor-3 is sufficient for lymphangiogenesis in transgenic mice
. EMBO J [Internet]. 2001;20(6):1223 - 31.
http://view.ncbi.nlm.nih.gov/pubmed/11250889
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Tanja Veikkola et al., EMBO Journal 2001
(491.14 KB)
T
Tvorogov D
,
Anisimov A
,
Zheng W
,
Leppänen V-M
,
Tammela T
,
Laurinavicius S
, et al.
.
Effective suppression of vascular network formation by combination of antibodies blocking VEGFR ligand binding and receptor dimerization
. Cancer Cell [Internet]. 2010;18(6):630 - 40.
http://view.ncbi.nlm.nih.gov/pubmed/21130043
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Denis Tvorogov et al., Cancer Cell 2010
(1.3 MB)
Denis Tvorogov et al., Cancer Cell 2010, supplement
(828.69 KB)
Tammela T
,
He Y
,
Lyytikkä J
,
Jeltsch M
,
Markkanen J
,
Pajusola K
, et al.
.
Distinct architecture of lymphatic vessels induced by chimeric vascular endothelial growth factor-C/vascular endothelial growth factor heparin-binding domain fusion proteins
. Circ Res [Internet]. 2007;100(10):1468 - 75.
http://view.ncbi.nlm.nih.gov/pubmed/17478733
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Tuomas Tammela et al., Circulation Research 2007
(1.1 MB)
S
Saharinen P
,
Helotera H
,
Miettinen J
,
Norrmen C
,
D'Amico G
,
Jeltsch M
, et al.
.
Claudin-like protein 24 interacts with the VEGFR-2 and VEGFR-3 pathways and regulates lymphatic vessel development
. Genes Dev [Internet]. 2010;24(9):875 - 80.
http://view.ncbi.nlm.nih.gov/pubmed/20439428
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Pipsa Saharinen et al., Genes & Development 2010
(1.2 MB)
Pipsa Saharinen et al., Genes & Development 2010, supplement
(9.15 MB)
Saaristo A
,
Veikkola T
,
Enholm B
,
Hytönen M
,
Arola J
,
Pajusola K
, et al.
.
Adenoviral VEGF-C overexpression induces blood vessel enlargement, tortuosity, and leakiness but no sprouting angiogenesis in the skin or mucous membranes
. FASEB J [Internet]. 2002;16(9):1041 - 9.
http://view.ncbi.nlm.nih.gov/pubmed/12087065
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Anne Saaristo et al., FASEB Journal 2002
(966.08 KB)
R
Rauniyar K
,
Bokharaie H
,
Jeltsch M
.
Expansion and collapse of VEGF diversity in major clades of the animal kingdom
. Angiogenesis [Internet]. 2023;26(3):437 - 461.
https://link.springer.com/10.1007/s10456-023-09874-9
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Rauniyar et al. - 2023 - Expansion and collapse of VEGF diversity in major clades of the animal kingdom
(3.59 MB)
Rauniyar K
.
VEGF-C: The evolutionary origin, activation, and potential as a drug target
[Internet]. [Helsinki. Finland]: University of Helsinki; 2023.
http://hdl.handle.net/10138/357923
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Rauniyar - 2023 - VEGF-C: The evolutionary origin, activation, and potential as a drug target
(3.09 MB)
Rauniyar K
,
Akhondzadeh S
,
Gąciarz A
,
Künnapuu J
,
Jeltsch M
.
Bioactive VEGF-C from E. coli
. Scientific Reports [Internet]. 2022;12(1).
https://www.nature.com/articles/s41598-022-22960-0
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Rauniyar et al. - 2022 - Bioactive VEGF-C from E. coli
(4.19 MB)
P
Pepper MS
,
Mandriota SJ
,
Jeltsch M
,
Kumar V
,
Alitalo K
.
Vascular endothelial growth factor (VEGF)-C synergizes with basic fibroblast growth factor and VEGF in the induction of angiogenesis in vitro and alters endothelial cell extracellular proteolytic activity
. J Cell Physiol [Internet]. 1998;177(3):439 - 52.
http://view.ncbi.nlm.nih.gov/pubmed/9808152
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Michael Pepper et al., Journal of Cellular Physiology 1998
(689.97 KB)
Panara V
,
Varaliová Z
,
Wilting J
,
Koltowska K
,
Jeltsch M
.
The relationship between the secondary vascular system and the lymphatic vascular system in fish
. Biological Reviews [Internet]. 2024;.
https://onlinelibrary.wiley.com/doi/10.1111/brv.13114
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Panara et al. - 2024 - The relationship between the secondary vascular system and the lymphatics vascular system in fish
(3.51 MB)
O
Olofsson B
,
Jeltsch M
,
Eriksson U
,
Alitalo K
.
Current biology of VEGF-B and VEGF-C
. Curr Opin Biotechnol [Internet]. 1999;10(6):528 - 35.
http://view.ncbi.nlm.nih.gov/pubmed/10600689
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Birgitta Olofsson et al., Current Opinion in Biotechnology 1999
(577.33 KB)
Olofsson B
,
Korpelainen E
,
Pepper MS
,
Mandriota SJ
,
Aase K
,
Kumar V
, et al.
.
Vascular endothelial growth factor B (VEGF-B) binds to VEGF receptor-1 and regulates plasminogen activator activity in endothelial cells
. Proc Natl Acad Sci U S A [Internet]. 1998;95(20):11709 - 14.
http://view.ncbi.nlm.nih.gov/pubmed/9751730
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Birgitta Olofsson et al., PNAS 1998
(470.59 KB)
Oh SJ
,
Jeltsch MM
,
Birkenhäger R
,
McCarthy JE
,
Weich HA
,
Christ B
, et al.
.
VEGF and VEGF-C: specific induction of angiogenesis and lymphangiogenesis in the differentiated avian chorioallantoic membrane
. Dev Biol [Internet]. 1997;188(1):96 - 109.
http://view.ncbi.nlm.nih.gov/pubmed/9245515
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Su-Ja Oh et al., Developmental Biology 1997
(3.28 MB)
M
Mandriota SJ
,
Jussila L
,
Jeltsch M
,
Compagni A
,
Baetens D
,
Prevo R
, et al.
.
Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis
. EMBO J [Internet]. 2001;20(4):672 - 82.
http://view.ncbi.nlm.nih.gov/pubmed/11179212
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Stefano Mandriota et al., EMBO Journal 2001
(736.96 KB)
L
López-Cerdá S
,
Molinaro G
,
ParejaTello R
,
Correia A
,
Künig S
,
Steinberger P
, et al.
.
Study of the Synergistic Immunomodulatory and Antifibrotic Effects of Dual-Loaded Budesonide and Serpine1 siRNA Lipid–Polymer Nanoparticles Targeting Macrophage Dysregulation in Tendinopathy
. ACS Applied Materials & Interfaces [Internet]. 2024;16(15):18643 - 18657.
https://pubs.acs.org/doi/10.1021/acsami.4c02363
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López-Cerdá et al. - 2024 - Study of the Synergistic Immunomodulatory and Antifibrotic Effects of Dual-Loaded Budesonide [...]
(7.06 MB)
Li X
,
Tjwa M
,
Van Hove I
,
Enholm B
,
Neven E
,
Paavonen K
, et al.
.
Reevaluation of the role of VEGF-B suggests a restricted role in the revascularization of the ischemic myocardium
. Arterioscler Thromb Vasc Biol [Internet]. 2008;28(9):1614 - 20.
http://view.ncbi.nlm.nih.gov/pubmed/18511699
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Xuri Li et al., Arteriosclerosis, Thrombosis, and Vascular Biology 2008
(738.26 KB)
Xuri Li et al., Arteriosclerosis, Thrombosis, and Vascular Biology 2008, data supplement
(1012.6 KB)
Leppänen V-M
,
Jeltsch M
,
Anisimov A
,
Tvorogov D
,
Aho K
,
Kalkkinen N
, et al.
.
Structural determinants of vascular endothelial growth factor-D receptor binding and specificity
. Blood [Internet]. 2011;117(5):1507 - 15.
http://view.ncbi.nlm.nih.gov/pubmed/21148085
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Veli-Matti Leppänen & Michael Jeltsch et al., Blood 2011
(1.17 MB)
Veli-Matti Leppänen & Michael Jeltsch et al. Blood 2011, supplementary data
(342.97 KB)
Leppänen V-M
,
Prota AE
,
Jeltsch M
,
Anisimov A
,
Kalkkinen N
,
Strandin T
, et al.
.
Structural determinants of growth factor binding and specificity by VEGF receptor 2
. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2010;107(6):2425 - 30.
http://view.ncbi.nlm.nih.gov/pubmed/20145116
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Veli-Matti Leppänen et al. PNAS 2010
(1 MB)
Veli-Matti Leppänen et al. PNAS 2010, supporting information
(2.23 MB)
Lackner M
,
Schmotz C
,
Jeltsch M
.
The Proteolytic Activation of Vascular Endothelial Growth Factor-C
. Lymphologie in Forschung und Praxis [Internet]. 2019;23(2):88 - 98.
https://doi.org/10.5281/zenodo.3629263
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English version: Lackner et al. 2019
(2.94 MB)
German version: Lackner et al. 2019
(673.37 KB)
K
Künnapuu J
,
Bokharaie H
,
Jeltsch M
.
Proteolytic Cleavages in the VEGF Family: Generating Diversity among Angiogenic VEGFs, Essential for the Activation of Lymphangiogenic VEGFs
. Biology [Internet]. 2021;10(2):167.
https://www.mdpi.com/2079-7737/10/2/167
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Künnapuu et al. - 2021 - Proteolytic Cleavages in the VEGF Family: Generating Diversity among Angiogenic VEGFs, Essential [...]
(3.44 MB)
Künnapuu J
,
Jeltsch M
.
Outside in and brakes off for lymphatic growth
. Science Signaling [Internet]. 2021;14(695).
https://www.science.org/doi/10.1126/scisignal.abj5058
DOI
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Künnapuu and Jeltsch - 2021 - Outside in and brakes off for lymphatic growth
(268.05 KB)
Kukk E
,
Lymboussaki A
,
Taira S
,
Kaipainen A
,
Jeltsch M
,
Joukov V
, et al.
.
VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development
. Development [Internet]. 1996;122(12):3829 - 37.
http://view.ncbi.nlm.nih.gov/pubmed/9012504
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Eola Kukk et al., Development 1996
(805.94 KB)
Krebs R
,
Jeltsch M
.
Die lymphangiogenic growth factors VEGF-C and VEGF-D. Part 2: The role of VEGF-C and VEGF-D in diseases of the lymphatic system. [bilingual: English, German].
Lymphologie in Forschung und Praxis [Internet]. 2013;17(2):96 - 104.
http://jeltsch.org/sites/jeltsch.org/files/JeltschMichael_Lymphforsch2013_96.pdf
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Krebs & Jeltsch (2013): The lymphangiogenic growth factors VEGF-C and VEGF-D. Part 2: The role of VEGF-C and VEGF-D in diseas...
(3.88 MB)
Krebs & Jeltsch (2013): Die lymphangiogenen Wachstumsfaktoren VEGF-C und VEGF-D. Teil 2. Die Rolle von VEGF-C und VEGF-D bei ...
(2.6 MB)
Krebs R
,
Tikkanen JM
,
Ropponen JO
,
Jeltsch M
,
Jokinen JJ
,
Ylä-Herttuala S
, et al.
.
VEGF-C/VEGFR-3 Signaling Regulates Inflammatory Response in Development of Obliterative Airway Disease
. Journal of Heart and Lung Transplantation. 2011;30:S118 - S118.
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