On the Lymphologica 2017 (Lymphologie 2017) congress in Bad Soden (Oct. 5-7, Frankfurt, Germany), I presented an introduction to the molecular biology of VEGF-C and how mutations in the genes of the VEGF-C/VEGFR-3 signaling axis can cause or contribute to hereditary lymphedema. The talk was targeted at healthcare practitioners who work in the lymphology field. A short review based on this talk was published in Vasomed and is available online.