VEGFR-3

Research into the molecular basis of lymphangiogenesis in embryonic development and pathological processes has led to a rapid increase of our knowledge (Krebs and Jeltsch 2013A, 2013B). The molecular biology era of lymphatic research began with the discovery of the VEGF growth factors and their receptors 25 years ago, and these molecules are the focus of this overview.

All cells in our body need oxygen and they receive it via the circulating blood. That's why the vascular system is the first organ system to function in a developing embryo.